antibody

FineTest(R)700 Anti-Human CD45 Antibody(HI30)

F700-30039

20T/100T

106/242 USD

monoclonal

mouse

nonconjugated

HI30

FineTest(R)700 Anti-Human CD45 Antibody(HI30)

Flow cytometry Antibodies

Mouse

Monoclonal

FineTest(R)700

HI30

20T/100T

106/242 USD

CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

CD45 L-CA Ly-5 Ptprc Receptor-type tyrosine-protein phosphatase C T200

Human CD45

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)