antibody

FineTest(R)700 Anti-Mouse CD8a Antibody(53-6.7)

F700-30003

50T/100T

70/112 USD

monoclonal

rat

nonconjugated

53-6.7

FineTest(R)700 Anti-Mouse CD8a Antibody(53-6.7)

Flow cytometry Antibodies

Rat

Monoclonal

FineTest(R)700

53-6.7

50T/100T

70/112 USD

CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked ? and ? chains that form the ?(CD8a)/?(CD8b) heterodimer and ?/? homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 ?/? heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR ?/? T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 ?/? homodimer is expressed on a subset of ?/? TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

CD8A MAL T-cell surface glycoprotein CD8 alpha chain T-lymphocyte differentiation antigen T8/Leu-2

Mouse CD8a

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)