antibody

FineTest(R)488 Anti-Human CD127/IL-7RA Antibody(A019D5)

F488-30033

20T/100T

246/612 USD

monoclonal

mouse

nonconjugated

A019D5

FineTest(R)488 Anti-Human CD127/IL-7RA Antibody(A019D5)

Flow cytometry Antibodies

Mouse

Monoclonal

FineTest(R)488

A019D5

20T/100T

246/612 USD

CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor ? chain or IL-7R?. It forms a heterodimer with the common ? chain (?c or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

CD127 CDw127 IL-7RA IL-7R? Interleukin-7 receptor subunit alpha

Human CD127/IL

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)