Arinrad S, Wilke J, Seelbach A, Doeren J, Hindermann M, Butt U, et al. NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance. Mol Psychiatry. 2021;: pubmed publisher

Sato K, Sato T, Ohno Oishi M, Ozawa M, Maekawa S, Shiga Y, et al. CHOP deletion and anti-neuroinflammation treatment with hesperidin synergistically attenuate NMDA retinal injury in mice. Exp Eye Res. 2021;213:108826 pubmed publisher

Wang T, Zhou P, Xie X, Tomita Y, Cho S, Tsirukis D, et al. Myeloid lineage contributes to pathological choroidal neovascularization formation via SOCS3. EBioMedicine. 2021;73:103632 pubmed publisher

Klammer M, Dzaye O, Wallach T, Krüger C, Gaessler D, Buonfiglioli A, et al. UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b. Front Immunol. 2021;12:715774 pubmed publisher

Pankiewicz J, Lizińczyk A, Franco L, Díaz J, Martá Ariza M, Sadowski M. Absence of Apolipoprotein E is associated with exacerbation of prion pathology and promotes microglial neurodegenerative phenotype. Acta Neuropathol Commun. 2021;9:157 pubmed publisher

Papazian I, Tsoukala E, Boutou A, Karamita M, Kambas K, Iliopoulou L, et al. Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice. J Neuroinflammation. 2021;18:222 pubmed publisher

Zhang P, Ohkawa Y, Yamamoto S, Momota H, Kato A, Kaneko K, et al. St8sia1-deficiency in mice alters tumor environments of gliomas, leading to reduced disease severity. Nagoya J Med Sci. 2021;83:535-549 pubmed publisher

Xiao Y, Liang J, Gao M, Sun J, Liu Y, Chen J, et al. Deletion of prominin-1 in mice results in disrupted photoreceptor outer segment protein homeostasis. Int J Ophthalmol. 2021;14:1334-1344 pubmed publisher

Yang C, Lei L, Collins J, Briones M, Ma L, Sturdevant G, et al. Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor. Nat Commun. 2021;12:5454 pubmed publisher

Weigelt C, Fuchs H, Schonberger T, Stierstorfer B, Strobel B, Lamla T, et al. AAV-Mediated Expression of Human VEGF, TNF-α, and IL-6 Induces Retinal Pathology in Mice. Transl Vis Sci Technol. 2021;10:15 pubmed publisher

Keane L, Cheray M, Saidi D, Kirby C, Friess L, González Rodríguez P, et al. Inhibition of microglial EZH2 leads to anti-tumoral effects in pediatric diffuse midline gliomas. Neurooncol Adv. 2021;3:vdab096 pubmed publisher

Zin E, Han D, Tran J, Morisson Welch N, Visel M, Kuronen M, et al. Outcomes of progranulin gene therapy in the retina are dependent on time and route of delivery. Mol Ther Methods Clin Dev. 2021;22:40-51 pubmed publisher

Blot F, Krijnen W, den Hoedt S, Osório C, White J, Mulder M, et al. Sphingolipid metabolism governs Purkinje cell patterned degeneration in Atxn1[82Q]/+ mice. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher

Solano Fonseca R, Metang P, Egge N, Liu Y, Zuurbier K, Sivaprakasam K, et al. Glycolytic preconditioning in astrocytes mitigates trauma-induced neurodegeneration. elife. 2021;10: pubmed publisher

Wu Y, Shao W, Todd T, Tong J, Yue M, Koga S, et al. Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD. Cell Rep. 2021;36:109581 pubmed publisher

Soldati C, Lopez Fabuel I, Wanderlingh L, García Macia M, Monfregola J, Esposito A, et al. Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype. EMBO Mol Med. 2021;13:e13742 pubmed publisher

Wehn A, Khalin I, Duering M, Hellal F, Culmsee C, Vandenabeele P, et al. RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury. Acta Neuropathol Commun. 2021;9:138 pubmed publisher

Lee S, Yang H, Sung Y, Kim Y, Park S. Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury. Exp Neurobiol. 2021;30:285-293 pubmed publisher

Sugiyama T, Murao N, Kadowaki H, Takao K, Miyakawa T, Matsushita Y, et al. ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function. iScience. 2021;24:102758 pubmed publisher

Miyajima H, Itokazu T, Tanabe S, Yamashita T. Interleukin-17A regulates ependymal cell proliferation and functional recovery after spinal cord injury in mice. Cell Death Dis. 2021;12:766 pubmed publisher

Jeong A, Cheng S, Zhong R, Bennett D, Bergo M, Li L. Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice. Acta Neuropathol Commun. 2021;9:129 pubmed publisher

Takahashi K, Nakamura S, Otsu W, Shimazawa M, Hara H. Progranulin deficiency in Iba-1+ myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation. J Neuroinflammation. 2021;18:164 pubmed publisher

Credendino S, De Menna M, Cantone I, Moccia C, Esposito M, Di Guida L, et al. FOXE1-Dependent Regulation of Macrophage Chemotaxis by Thyroid Cells In Vitro and In Vivo. Int J Mol Sci. 2021;22: pubmed publisher

Lin Z, Chen C, Yang D, Ding J, Wang G, Ren H. DJ-1 inhibits microglial activation and protects dopaminergic neurons in vitro and in vivo through interacting with microglial p65. Cell Death Dis. 2021;12:715 pubmed publisher

Benitez D, Jiang S, Wood J, Wang R, Hall C, Peerboom C, et al. Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia. Mol Neurodegener. 2021;16:47 pubmed publisher

Olson B, Zhu X, Norgard M, Diba P, Levasseur P, Buenafe A, et al. Chronic cerebral lipocalin 2 exposure elicits hippocampal neuronal dysfunction and cognitive impairment. Brain Behav Immun. 2021;97:102-118 pubmed publisher

Li D, Edwards R, Manne K, Martinez D, Schäfer A, Alam S, et al. In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell. 2021;184:4203-4219.e32 pubmed publisher

Aranda J, Fernández Arjona M, Alen F, Rivera P, Rubio L, Smith Fernández I, et al. Sudden cessation of fluoxetine before alcohol drinking reinstatement alters microglial morphology and TLR4/inflammatory neuroadaptation in the rat brain. Brain Struct Funct. 2021;226:2243-2264 pubmed publisher

Gaja Capdevila N, Hernández N, Zamanillo D, Vela J, Merlos M, Navarro X, et al. Neuroprotective Effects of Sigma 1 Receptor Ligands on Motoneuron Death after Spinal Root Injury in Mice. Int J Mol Sci. 2021;22: pubmed publisher

Emre C, Do K, Jun B, Hjorth E, Alcalde S, Kautzmann M, et al. Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:116 pubmed publisher

Wang Y, Su Y, Yu G, Wang X, Chen X, Yu B, et al. Reduced Oligodendrocyte Precursor Cell Impairs Astrocytic Development in Early Life Stress. Adv Sci (Weinh). 2021;8:e2101181 pubmed publisher

Liu D, Guo J, Su J, Svanbergsson A, Yuan L, Haikal C, et al. Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions. Transl Neurodegener. 2021;10:20 pubmed publisher

He X, Chandrashekar A, Zahn R, Wegmann F, Yu J, Mercado N, et al. Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques. Cell. 2021;184:3467-3473.e11 pubmed publisher

An L, Shen Y, Chopp M, Zacharek A, Venkat P, Chen Z, et al. Deficiency of Endothelial Nitric Oxide Synthase (eNOS) Exacerbates Brain Damage and Cognitive Deficit in A Mouse Model of Vascular Dementia. Aging Dis. 2021;12:732-746 pubmed publisher

Boehme N, Hedberg Buenz A, Tatro N, Bielecki M, Castonguay W, Scheetz T, et al. Axonopathy precedes cell death in ocular damage mediated by blast exposure. Sci Rep. 2021;11:11774 pubmed publisher

Keshvari S, Caruso M, Teakle N, Batoon L, Sehgal A, Patkar O, et al. CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS Genet. 2021;17:e1009605 pubmed publisher

Jiang X, Rashwan R, Voigt V, NERBONNE J, Hunt D, Carvalho L. Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K+ Channel Subunits Kv8.2 and K2.1. Int J Mol Sci. 2021;22: pubmed publisher

Galán Ganga M, Rodríguez Cueto C, Merchán Rubira J, Hernandez F, Avila J, Posada Ayala M, et al. Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration. Acta Neuropathol Commun. 2021;9:90 pubmed publisher

Bradshaw D, Knutsen A, Korotcov A, Sullivan G, Radomski K, Dardzinski B, et al. Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures. Acta Neuropathol Commun. 2021;9:89 pubmed publisher

Korotkov A, Sim N, Luinenburg M, Anink J, van Scheppingen J, Zimmer T, et al. MicroRNA-34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis. Neuropathol Appl Neurobiol. 2021;47:796-811 pubmed publisher

Li P, Lin Z, An Y, Lin J, Zhang A, Wang S, et al. Piccolo is essential for the maintenance of mouse retina but not cochlear hair cell function. Aging (Albany NY). 2021;13:11678-11695 pubmed publisher

Mu W, Li S, Xu J, Guo X, Wu H, Chen Z, et al. Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice. Nat Commun. 2021;12:2288 pubmed publisher

Huang Y, Happonen K, Burrola P, O Connor C, Hah N, Huang L, et al. Microglia use TAM receptors to detect and engulf amyloid β plaques. Nat Immunol. 2021;22:586-594 pubmed publisher

Oh B, Wu Y, Swaminathan V, Lam V, Ding J, George P. Modulating the Electrical and Mechanical Microenvironment to Guide Neuronal Stem Cell Differentiation. Adv Sci (Weinh). 2021;8:2002112 pubmed publisher

Colombo A, Sadler R, Llovera G, Singh V, Roth S, Heindl S, et al. Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition. elife. 2021;10: pubmed publisher

Gulbranson D, Ho K, Yu G, Yu X, Das M, Shao E, et al. Phenotypic Differences between the Alzheimer's Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice. Eneuro. 2021;8: pubmed publisher

Criado Marrero M, Gebru N, Blazier D, Gould L, Baker J, Beaulieu Abdelahad D, et al. Hsp90 co-chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild-type mice. Acta Neuropathol Commun. 2021;9:65 pubmed publisher

Rosa J, Farré Alins V, Ortega M, Navarrete M, López Rodríguez A, Palomino Antolin A, et al. TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury. Br J Pharmacol. 2021;178:3395-3413 pubmed publisher

Saunders D, Aamodt K, Richardson T, Hopkirk A, Aramandla R, Poffenberger G, et al. Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration. NPJ Regen Med. 2021;6:22 pubmed publisher

Bassal M, Liu J, Jankowiak W, Saftig P, Bartsch U. Rapid and Progressive Loss of Multiple Retinal Cell Types in Cathepsin D-Deficient Mice-An Animal Model of CLN10 Disease. Cells. 2021;10: pubmed publisher

Frew J, Nygaard H. Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun. 2021;9:57 pubmed publisher

Higgins N, Greenslade J, Wu J, Miranda E, Galliciotti G, Monteiro M. Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD. Brain Pathol. 2021;:e12948 pubmed publisher

Li Y, Ritchie E, Steinke C, Qi C, Chen L, Zheng B, et al. Activation of MAP3K DLK and LZK in Purkinje cells causes rapid and slow degeneration depending on signaling strength. elife. 2021;10: pubmed publisher

Yuan D, Cheng A, Kawahata I, Izumi H, Xu J, Fukunaga K. Single Administration of the T-Type Calcium Channel Enhancer SAK3 Reduces Oxidative Stress and Improves Cognition in Olfactory Bulbectomized Mice. Int J Mol Sci. 2021;22: pubmed publisher

Vandenabeele M, Veys L, Lemmens S, Hadoux X, Gelders G, Masin L, et al. The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research. Acta Neuropathol Commun. 2021;9:6 pubmed publisher

Sobue A, Komine O, Hara Y, Endo F, Mizoguchi H, Watanabe S, et al. Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:1 pubmed publisher

Thau Zuchman O, Svendsen L, Dyall S, Paredes Esquivel U, Rhodes M, Priestley J, et al. A new ketogenic formulation improves functional outcome and reduces tissue loss following traumatic brain injury in adult mice. Theranostics. 2021;11:346-360 pubmed publisher

Aggio Bruce R, Chu Tan J, Wooff Y, Cioanca A, Schumann U, Natoli R. Inhibition of microRNA-155 Protects Retinal Function Through Attenuation of Inflammation in Retinal Degeneration. Mol Neurobiol. 2021;58:835-854 pubmed publisher

Greferath U, Huynh M, Jobling A, Vessey K, Venables G, Surrao D, et al. Dorsal-Ventral Differences in Retinal Structure in the Pigmented Royal College of Surgeons Model of Retinal Degeneration. Front Cell Neurosci. 2020;14:553708 pubmed publisher

Biechele G, Franzmeier N, Blume T, Ewers M, Luque J, Eckenweber F, et al. Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases. J Neuroinflammation. 2020;17:374 pubmed publisher

Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv. 2020;6: pubmed publisher

Smith S, Chen X, Brier L, Bumstead J, Rensing N, Ringel A, et al. Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway. Nat Commun. 2020;11:6164 pubmed publisher

Lin L, Petralia R, Lake R, Wang Y, Hoffman D. A novel structure associated with aging is augmented in the DPP6-KO mouse brain. Acta Neuropathol Commun. 2020;8:197 pubmed publisher

Shin S, Cai Y, Itson Zoske B, Qiu C, Hao X, Xiang H, et al. Enhanced T-type calcium channel 3.2 activity in sensory neurons contributes to neuropathic-like pain of monosodium iodoacetate-induced knee osteoarthritis. Mol Pain. 2020;16:1744806920963807 pubmed publisher

Bengoa Vergniory N, Faggiani E, Ramos Gonzalez P, Kirkiz E, Connor Robson N, Brown L, et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nat Commun. 2020;11:4885 pubmed publisher

Scheckel C, Imeri M, Schwarz P, Aguzzi A. Ribosomal profiling during prion disease uncovers progressive translational derangement in glia but not in neurons. elife. 2020;9: pubmed publisher

Ifuku M, Hinkelmann L, Kuhrt L, Efe I, Kumbol V, Buonfiglioli A, et al. Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury. Acta Neuropathol Commun. 2020;8:159 pubmed publisher

Huang W, Bai X, Meyer E, Scheller A. Acute brain injuries trigger microglia as an additional source of the proteoglycan NG2. Acta Neuropathol Commun. 2020;8:146 pubmed publisher

Yang C, Kari L, Lei L, Carlson J, Ma L, Couch C, et al. Chlamydia trachomatis Plasmid Gene Protein 3 Is Essential for the Establishment of Persistent Infection and Associated Immunopathology. MBio. 2020;11: pubmed publisher

Cignarella F, Filipello F, Bollman B, Cantoni C, Locca A, Mikesell R, et al. TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis. Acta Neuropathol. 2020;140:513-534 pubmed publisher

Ueno H, Shimada A, Suemitsu S, Murakami S, Kitamura N, Wani K, et al. Alpha-pinene and dizocilpine (MK-801) attenuate kindling development and astrocytosis in an experimental mouse model of epilepsy. IBRO Rep. 2020;9:102-114 pubmed publisher

Moreno Valladares M, Moreno Cugnon L, Silva T, Garcés J, Sáenz Antoñanzas A, Álvarez Satta M, et al. CD8+ T cells are increased in the subventricular zone with physiological and pathological aging. Aging Cell. 2020;:e13198 pubmed publisher

Pu A, Mishra M, Dong Y, Ghorbanigazar S, Stephenson E, Rawji K, et al. The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination. J Neuroinflammation. 2020;17:220 pubmed publisher

Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher

Chi Y, Remšík J, Kiseliovas V, Derderian C, Sener U, Alghader M, et al. Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis. Science. 2020;369:276-282 pubmed publisher

Tang S, Fesharaki Zadeh A, Takahashi H, Nies S, Smith L, Luo A, et al. Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy. Acta Neuropathol Commun. 2020;8:96 pubmed publisher

Wander C, Tseng J, Song S, Al Housseiny H, Tart D, Ajit A, et al. The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging. iScience. 2020;23:101255 pubmed publisher

Yu X, Pandey K, Katzman A, Alberini C. A role for CIM6P/IGF2 receptor in memory consolidation and enhancement. elife. 2020;9: pubmed publisher

LeBlang C, Medalla M, Nicoletti N, Hays E, Zhao J, Shattuck J, et al. Reduction of the RNA Binding Protein TIA1 Exacerbates Neuroinflammation in Tauopathy. Front Neurosci. 2020;14:285 pubmed publisher

Gee M, Son S, Jeon S, Do J, Kim N, Ju Y, et al. A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse. Alzheimers Res Ther. 2020;12:45 pubmed publisher

Rauch J, Luna G, Guzman E, Audouard M, Challis C, Sibih Y, et al. LRP1 is a master regulator of tau uptake and spread. Nature. 2020;580:381-385 pubmed publisher

Tisi A, Parete G, Flati V, Maccarone R. Up-regulation of pro-angiogenic pathways and induction of neovascularization by an acute retinal light damage. Sci Rep. 2020;10:6376 pubmed publisher

Salido E, Ramamurthy V. Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision. J Neurosci. 2020;40:4059-4072 pubmed publisher

Yang X, Zhao L, Campos M, Abu Asab M, Ortolan D, Hotaling N, et al. CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization. elife. 2020;9: pubmed publisher

Mecha M, Yanguas Casás N, Feliú A, Mestre L, Carrillo Salinas F, Riecken K, et al. Involvement of Wnt7a in the role of M2c microglia in neural stem cell oligodendrogenesis. J Neuroinflammation. 2020;17:88 pubmed publisher

Williams B, Lees F, Tsangari H, Hutchinson M, Perilli E, Crotti T. Assessing the Effects of Parthenolide on Inflammation, Bone Loss, and Glial Cells within a Collagen Antibody-Induced Arthritis Mouse Model. Mediators Inflamm. 2020;2020:6245798 pubmed publisher

Chan K, Nestor J, Huerta T, Certain N, Moody G, Kowal C, et al. Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory. Nat Commun. 2020;11:1403 pubmed publisher

Kur I, Prouvot P, Fu T, Fan W, Müller Braun F, Das A, et al. Neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo. PLoS Biol. 2020;18:e3000643 pubmed publisher

Martínez González L, Rodríguez Cueto C, Cabezudo D, Bartolomé F, Andrés Benito P, Ferrer I, et al. Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment. Sci Rep. 2020;10:4449 pubmed publisher

Yoshino M, Saito K, Kawasaki K, Horiike T, Shinmyo Y, Kawasaki H. The origin and development of subcortical U-fibers in gyrencephalic ferrets. Mol Brain. 2020;13:37 pubmed publisher

Yagura K, Ohtaki H, Tsumuraya T, Sato A, Miyamoto K, Kawada N, et al. The enhancement of CCL2 and CCL5 by human bone marrow-derived mesenchymal stem/stromal cells might contribute to inflammatory suppression and axonal extension after spinal cord injury. PLoS ONE. 2020;15:e0230080 pubmed publisher

Stein L, Lhamo R, Cao A, Workinger J, TINSLEY I, Doyle R, et al. Dorsal vagal complex and hypothalamic glia differentially respond to leptin and energy balance dysregulation. Transl Psychiatry. 2020;10:90 pubmed publisher

Yang H, Wang L, Zang C, Wang Y, Shang J, Zhang Z, et al. Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson's Disease Models. Front Neurosci. 2020;14:45 pubmed publisher

Shi H, Wang Q, Zheng M, Hao S, Lum J, Chen X, et al. Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice. J Neuroinflammation. 2020;17:77 pubmed publisher

Sardari M, Dzyubenko E, Schmermund B, Yin D, Qi Y, Kleinschnitz C, et al. Dose-Dependent Microglial and Astrocytic Responses Associated With Post-ischemic Neuroprotection After Lipopolysaccharide-Induced Sepsis-Like State in Mice. Front Cell Neurosci. 2020;14:26 pubmed publisher

Rambousek L, Gschwind T, Lafourcade C, Paterna J, Dib L, Fritschy J, et al. Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor. Sci Rep. 2020;10:3760 pubmed publisher

Wu Z, Parry M, Hou X, Liu M, Wang H, Cain R, et al. Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington's disease. Nat Commun. 2020;11:1105 pubmed publisher

Miyawaki T, Morikawa S, Susaki E, Nakashima A, Takeuchi H, Yamaguchi S, et al. Visualization and molecular characterization of whole-brain vascular networks with capillary resolution. Nat Commun. 2020;11:1104 pubmed publisher

Lu H, Kim S, Steelman A, Tracy K, Zhou B, Michaud D, et al. STAT3 signaling in myeloid cells promotes pathogenic myelin-specific T cell differentiation and autoimmune demyelination. Proc Natl Acad Sci U S A. 2020;117:5430-5441 pubmed publisher

Kosuge Y, Kaneko E, Nango H, Miyagishi H, Ishige K, Ito Y. Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. Oxid Med Cell Longev. 2020;2020:1020673 pubmed publisher

Sarkar S, Dammer E, Malovic E, Olsen A, Raza S, Gao T, et al. Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells. Front Immunol. 2020;11:33 pubmed publisher

Yang Y, He Z, Xing Z, Zuo Z, Yuan L, Wu Y, et al. Influenza vaccination in early Alzheimer's disease rescues amyloidosis and ameliorates cognitive deficits in APP/PS1 mice by inhibiting regulatory T cells. J Neuroinflammation. 2020;17:65 pubmed publisher

Barros Viegas A, Carmona V, Ferreiro E, Guedes J, Cardoso A, Cunha P, et al. miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer's Disease. Mol Ther Nucleic Acids. 2020;19:1219-1236 pubmed publisher

Ullah F, Asgarov R, Venigalla M, Liang H, Niedermayer G, Munch G, et al. Effects of a solid lipid curcumin particle formulation on chronic activation of microglia and astroglia in the GFAP-IL6 mouse model. Sci Rep. 2020;10:2365 pubmed publisher

Wooff Y, Fernando N, Wong J, Dietrich C, Aggio Bruce R, Chu Tan J, et al. Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration. Sci Rep. 2020;10:2263 pubmed publisher

Rawji K, Young A, Ghosh T, Michaels N, Mirzaei R, Kappen J, et al. Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta Neuropathol. 2020;139:893-909 pubmed publisher

Ali S, Mansour A, Huang W, Queen N, Mo X, Anderson J, et al. CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. Aging (Albany NY). 2020;12:2101-2122 pubmed publisher

Grovola M, Paleologos N, Wofford K, Harris J, Browne K, Johnson V, et al. Mossy cell hypertrophy and synaptic changes in the hilus following mild diffuse traumatic brain injury in pigs. J Neuroinflammation. 2020;17:44 pubmed publisher

Nomura Komoike K, Saitoh F, Fujieda H. Phosphatidylserine recognition and Rac1 activation are required for Müller glia proliferation, gliosis and phagocytosis after retinal injury. Sci Rep. 2020;10:1488 pubmed publisher

Meilandt W, Ngu H, Gogineni A, Lalehzadeh G, Lee S, Srinivasan K, et al. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model. J Neurosci. 2020;40:1956-1974 pubmed publisher

Yin Y, Pham T, Shin J, Shin N, Kang D, Lee S, et al. Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice. J Clin Med. 2020;9: pubmed publisher

Walker D, Tang T, Mendsaikhan A, Tooyama I, Serrano G, Sue L, et al. Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains. Int J Mol Sci. 2020;21: pubmed publisher

Sierksma A, Lu A, Mancuso R, Fattorelli N, Thrupp N, Salta E, et al. Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology. EMBO Mol Med. 2020;12:e10606 pubmed publisher

Linker K, Elabd M, Tawadrous P, Cano M, Green K, Wood M, et al. Microglial activation increases cocaine self-administration following adolescent nicotine exposure. Nat Commun. 2020;11:306 pubmed publisher

Lee T, Ahn J, Park C, Kim B, Park Y, Lee J, et al. Pre-Treatment with Laminarin Protects Hippocampal CA1 Pyramidal Neurons and Attenuates Reactive Gliosis Following Transient Forebrain Ischemia in Gerbils. Mar Drugs. 2020;18: pubmed publisher

Gao Y, Tu D, Yang R, Chu C, Hong J, Gao H. Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1β Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration. Int J Mol Sci. 2020;21: pubmed publisher

Yu X, Liu H, Hamel K, Morvan M, Yu S, Leff J, et al. Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. Nat Commun. 2020;11:264 pubmed publisher

Ozen I, Ruscher K, Nilsson R, Flygt J, Clausen F, Marklund N. Interleukin-1 Beta Neutralization Attenuates Traumatic Brain Injury-Induced Microglia Activation and Neuronal Changes in the Globus Pallidus. Int J Mol Sci. 2020;21: pubmed publisher

Evonuk K, Doyle R, Moseley C, Thornell I, Adler K, Bingaman A, et al. Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation. Sci Adv. 2020;6:eaax5936 pubmed publisher

Malhotra A, Castillo Melendez M, Allison B, Sutherland A, Nitsos I, Pham Y, et al. Neurovascular effects of umbilical cord blood-derived stem cells in growth-restricted newborn lambs : UCBCs for perinatal brain injury. Stem Cell Res Ther. 2020;11:17 pubmed publisher

He Z, McBride J, Xu H, Changolkar L, Kim S, Zhang B, et al. Transmission of tauopathy strains is independent of their isoform composition. Nat Commun. 2020;11:7 pubmed publisher

Anstötz M, Maccaferri G. A Toolbox of Criteria for Distinguishing Cajal-Retzius Cells from Other Neuronal Types in the Postnatal Mouse Hippocampus. Eneuro. 2020;7: pubmed publisher

Lee J, Jeon Y, Park S, Son C. An Adrenalectomy Mouse Model Reflecting Clinical Features for Chronic Fatigue Syndrome. Biomolecules. 2020;10: pubmed publisher

Bhattarai P, Cosacak M, Mashkaryan V, Demir S, Popova S, Govindarajan N, et al. Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain. PLoS Biol. 2020;18:e3000585 pubmed publisher

Zhang L, Pan J, Mamtilahun M, Zhu Y, Wang L, Venkatesh A, et al. Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion. Theranostics. 2020;10:74-90 pubmed publisher

Tzameret A, Piontkewitz Y, Nitzan A, Rudoler N, Bruzel M, Zilberstein Y, et al. Mild carotid stenosis creates gradual, progressive, lifelong brain, and eye damage: An experimental laboratory rat model. J Comp Neurol. 2020;528:1672-1682 pubmed publisher

Lee J, Hall J, Kroehling L, Wu L, Najar T, Nguyen H, et al. Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease. Cell. 2020;180:79-91.e16 pubmed publisher

Streeter K, Sunshine M, Brant J, Sandoval A, Maden M, Fuller D. Molecular and histologic outcomes following spinal cord injury in spiny mice, Acomys cahirinus. J Comp Neurol. 2020;528:1535-1547 pubmed publisher

Chini M, Pöpplau J, Lindemann C, Carol Perdiguer L, Hnida M, Oberländer V, et al. Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment. Neuron. 2020;105:60-74.e7 pubmed publisher

N diaye M, Brauner S, Flytzani S, Kular L, Warnecke A, Adzemovic M, et al. C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation. J Clin Invest. 2020;130:838-852 pubmed publisher

Agostini A, Yuchun D, Li B, Kendall D, Pardon M. Sex-specific hippocampal metabolic signatures at the onset of systemic inflammation with lipopolysaccharide in the APPswe/PS1dE9 mouse model of Alzheimer's disease. Brain Behav Immun. 2020;83:87-111 pubmed publisher

Zhang R, Liu Y, Chen Y, Li Q, Marshall C, Wu T, et al. Aquaporin 4 deletion exacerbates brain impairments in a mouse model of chronic sleep disruption. CNS Neurosci Ther. 2020;26:228-239 pubmed publisher

Bader M, Li Y, Tweedie D, Shlobin N, Bernstein A, Rubovitch V, et al. Neuroprotective Effects and Treatment Potential of Incretin Mimetics in a Murine Model of Mild Traumatic Brain Injury. Front Cell Dev Biol. 2019;7:356 pubmed publisher

Kriszta G, Nemes B, Sandor Z, Acs P, Komoly S, Berente Z, et al. Investigation of Cuprizone-Induced Demyelination in mGFAP-Driven Conditional Transient Receptor Potential Ankyrin 1 (TRPA1) Receptor Knockout Mice. Cells. 2019;9: pubmed publisher

Wheeler J, McMillan P, Strovas T, Liachko N, Amlie Wolf A, Kow R, et al. Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain. Sci Transl Med. 2019;11: pubmed publisher

Moutal A, Kalinin S, Kowal K, Marangoni N, Dupree J, Lin S, et al. Neuronal Conditional Knockout of Collapsin Response Mediator Protein 2 Ameliorates Disease Severity in a Mouse Model of Multiple Sclerosis. ASN Neuro. 2019;11:1759091419892090 pubmed publisher

Mathiesen Janiurek M, Soylu Kucharz R, Christoffersen C, Kucharz K, Lauritzen M. Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis. elife. 2019;8: pubmed publisher

Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt S, Vieira Saecker A, et al. NLRP3 inflammasome activation drives tau pathology. Nature. 2019;: pubmed publisher

Rabenstein M, Unverricht Yeboah M, Keuters M, Pikhovych A, Hucklenbroich J, Vay S, et al. Transcranial Current Stimulation Alters the Expression of Immune-Mediating Genes. Front Cell Neurosci. 2019;13:461 pubmed publisher

Lummis N, Sánchez Pavón P, Kennedy G, Frantz A, Kihara Y, Blaho V, et al. LPA1/3 overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction. Sci Adv. 2019;5:eaax2011 pubmed publisher

Piatkevich K, Bensussen S, Tseng H, Shroff S, Lopez Huerta V, Park D, et al. Population imaging of neural activity in awake behaving mice. Nature. 2019;574:413-417 pubmed publisher

Grimaldi A, Pediconi N, Oieni F, Pizzarelli R, Rosito M, Giubettini M, et al. Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer's Disease Patients, Possible Biomarkers for Early Diagnosis. Front Neurosci. 2019;13:925 pubmed publisher

Ahn J, Kim D, Park J, Lee T, Lee H, Won M, et al. Expression changes of CX3CL1 and CX3CR1 proteins in the hippocampal CA1 field of the gerbil following transient global cerebral ischemia. Int J Mol Med. 2019;44:939-948 pubmed publisher

Suh J, Romano D, Nitschke L, Herrick S, DiMarzio B, Dzhala V, et al. Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription. Cell. 2019;178:1159-1175.e17 pubmed publisher

Wirsching H, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino P, et al. Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma. JCI Insight. 2019;4: pubmed publisher

Ghosh A, Torraville S, Mukherjee B, Walling S, Martin G, Harley C, et al. An experimental model of Braak's pretangle proposal for the origin of Alzheimer's disease: the role of locus coeruleus in early symptom development. Alzheimers Res Ther. 2019;11:59 pubmed publisher

Lee F, Lai T, Su P, Liu F. Altered cortical Cytoarchitecture in the Fmr1 knockout mouse. Mol Brain. 2019;12:56 pubmed publisher

Andoh M, Shibata K, Okamoto K, Onodera J, Morishita K, Miura Y, et al. Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation. Cell Rep. 2019;27:2817-2825.e5 pubmed publisher

Butti E, Bacigaluppi M, Chaabane L, Ruffini F, Brambilla E, Berera G, et al. Neural stem cells of the subventricular zone contribute to neuroprotection of the corpus callosum after cuprizone-induced demyelination. J Neurosci. 2019;: pubmed publisher

Anderson S, Roberts J, Zhang J, Steele M, Romero C, Bosco A, et al. Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia. Cell Rep. 2019;27:2002-2013.e5 pubmed publisher

Duan W, Guo M, Yi L, Zhang J, Bi Y, Liu Y, et al. Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice. Aging (Albany NY). 2019;11:2457-2476 pubmed publisher

Kyle J, Wu M, Gourzi S, Tsirka S. Proliferation and Differentiation in the Adult Subventricular Zone Are Not Affected by CSF1R Inhibition. Front Cell Neurosci. 2019;13:97 pubmed publisher

Vrselja Z, Daniele S, Silbereis J, Talpo F, Morozov Y, Sousa A, et al. Restoration of brain circulation and cellular functions hours post-mortem. Nature. 2019;568:336-343 pubmed publisher

Eisemann T, Costa B, Peterziel H, Angel P. Podoplanin Positive Myeloid Cells Promote Glioma Development by Immune Suppression. Front Oncol. 2019;9:187 pubmed publisher

Zhang P, Kishimoto Y, Grammatikakis I, Gottimukkala K, Cutler R, Zhang S, et al. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model. Nat Neurosci. 2019;22:719-728 pubmed publisher

Vogel S, Schäfer C, Hess S, Folz Donahue K, Nelles M, Minassian A, et al. The in vivo timeline of differentiation of engrafted human neural progenitor cells. Stem Cell Res. 2019;37:101429 pubmed publisher

Bieri G, Brahic M, Bousset L, Couthouis J, Kramer N, Ma R, et al. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. Acta Neuropathol. 2019;137:961-980 pubmed publisher

Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, et al. Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model. Nat Commun. 2019;10:1365 pubmed publisher

Hocker A, Beyeler S, Gardner A, Johnson S, Watters J, Huxtable A. One bout of neonatal inflammation impairs adult respiratory motor plasticity in male and female rats. elife. 2019;8: pubmed publisher

Martorell A, Paulson A, Suk H, Abdurrob F, Drummond G, Guan W, et al. Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell. 2019;177:256-271.e22 pubmed publisher

Carballo Carbajal I, Laguna A, Romero Gimenez J, Cuadros T, Bove J, Martinez Vicente M, et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis. Nat Commun. 2019;10:973 pubmed publisher

Willard A, Isett B, Whalen T, Mastro K, Ki C, Mao X, et al. State transitions in the substantia nigra reticulata predict the onset of motor deficits in models of progressive dopamine depletion in mice. elife. 2019;8: pubmed publisher

Pan R, Ma J, Kong X, Wang X, Li S, Qi X, et al. Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance. Sci Adv. 2019;5:eaau6328 pubmed publisher

Joy M, Ben Assayag E, Shabashov Stone D, Liraz Zaltsman S, Mazzitelli J, Arenas M, et al. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell. 2019;176:1143-1157.e13 pubmed publisher

Koike T, Tanaka S, Hirahara Y, Oe S, Kurokawa K, Maeda M, et al. Morphological characteristics of p75 neurotrophin receptor-positive cells define a new type of glial cell in the rat dorsal root ganglia. J Comp Neurol. 2019;527:2047-2060 pubmed publisher

Ling S, Dastidar S, Tokunaga S, Ho W, Lim K, Ilieva H, et al. Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. elife. 2019;8: pubmed publisher

Rosenzweig N, Dvir Szternfeld R, Tsitsou Kampeli A, Keren Shaul H, Ben Yehuda H, Weill Raynal P, et al. PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model. Nat Commun. 2019;10:465 pubmed publisher

Ma W, Silverman S, Zhao L, Villasmil R, Campos M, Amaral J, et al. Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization. elife. 2019;8: pubmed publisher

Cheng W, Martens K, Bashir A, Cheung H, Stukas S, Gibbs E, et al. CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice. Alzheimers Res Ther. 2019;11:6 pubmed publisher

Jassim A, Inman D. Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension. Invest Ophthalmol Vis Sci. 2019;60:1-15 pubmed publisher

Stojic A, Bojcevski J, Williams S, Bas Orth C, Nessler S, Linington C, et al. Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis. Glia. 2019;67:512-524 pubmed publisher

Noctor S, Penna E, Shepherd H, Chelson C, Barger N, Mart nez Cerde o V, et al. Periventricular microglial cells interact with dividing precursor cells in the nonhuman primate and rodent prenatal cerebral cortex. J Comp Neurol. 2019;527:1598-1609 pubmed publisher

Gibson E, Nagaraja S, Ocampo A, Tam L, Wood L, Pallegar P, et al. Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment. Cell. 2019;176:43-55.e13 pubmed publisher

Salazar S, Cox T, Lee S, Brody A, Chyung A, Haas L, et al. Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β-Induced Synaptic Dysfunction and Loss. J Neurosci. 2019;39:758-772 pubmed publisher

Zeiner P, Preusse C, Golebiewska A, Zinke J, Iriondo A, Muller A, et al. Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas. Brain Pathol. 2019;29:513-529 pubmed publisher

Hill J, Zuluaga Ramirez V, Gajghate S, Winfield M, Sriram U, Rom S, et al. Activation of GPR55 induces neuroprotection of hippocampal neurogenesis and immune responses of neural stem cells following chronic, systemic inflammation. Brain Behav Immun. 2019;76:165-181 pubmed publisher

Yoshimoto R, Aijima R, Ohyama Y, Yoshizumi J, Kitsuki T, Ohsaki Y, et al. Impaired Junctions and Invaded Macrophages in Oral Epithelia With Oral Pain. J Histochem Cytochem. 2019;67:245-256 pubmed publisher

Oh H, Paik J. Genetic Ablation of FOXO in Mice to Investigate Its Physiological Role. Methods Mol Biol. 2019;1890:239-248 pubmed publisher

Zrzavy T, Hoftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, et al. Pro-inflammatory activation of microglia in the brain of patients with sepsis. Neuropathol Appl Neurobiol. 2019;45:278-290 pubmed publisher

Zhao Y, Sun X, Qi X. Inhibition of Drp1 hyperactivation reduces neuropathology and behavioral deficits in zQ175 knock-in mouse model of Huntington's disease. Biochem Biophys Res Commun. 2018;507:319-323 pubmed publisher

Aloni E, Ruggiero A, Gross A, Segal M. Learning Deficits in Adult Mitochondria Carrier Homolog 2 Forebrain Knockout Mouse. Neuroscience. 2018;394:156-163 pubmed publisher

Zhang C, Jiang M, Zhou H, Liu W, Wang C, Kang Z, et al. TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation. J Clin Invest. 2018;128:5399-5412 pubmed publisher

López Erauskin J, Tadokoro T, Baughn M, Myers B, McAlonis Downes M, Chillon Marinas C, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018;100:816-830.e7 pubmed publisher

Atkins C, Miao J, Kalveram B, Juelich T, Smith J, Perez D, et al. Natural History and Pathogenesis of Wild-Type Marburg Virus Infection in STAT2 Knockout Hamsters. J Infect Dis. 2018;218:S438-S447 pubmed publisher

Borowska Fielding J, Murataeva N, Smith B, Szczesniak A, Leishman E, Daily L, et al. Revisiting cannabinoid receptor 2 expression and function in murine retina. Neuropharmacology. 2018;141:21-31 pubmed publisher

Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed publisher

Oliveira A, Sharma R, Aquino V, Lobaton G, Bryant A, Harrison J, et al. Involvement of Microglial Cells in Hypoxia-induced Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2018;59:271-273 pubmed publisher

Kiang L, Ross B, Yao J, Shanmugam S, Andrews C, Hansen S, et al. Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment. Invest Ophthalmol Vis Sci. 2018;59:3767-3778 pubmed publisher

Bang S, Xie Y, Zhang Z, Wang Z, Xu Z, Ji R. GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain. J Clin Invest. 2018;128:3568-3582 pubmed publisher

Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed publisher

Giera S, Luo R, Ying Y, Ackerman S, Jeong S, Stoveken H, et al. Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells. elife. 2018;7: pubmed publisher

Reichenbach N, Delekate A, Breithausen B, Keppler K, Poll S, Schulte T, et al. P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model. J Exp Med. 2018;215:1649-1663 pubmed publisher

Wendeln A, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, et al. Innate immune memory in the brain shapes neurological disease hallmarks. Nature. 2018;556:332-338 pubmed publisher

Mironets E, Osei Owusu P, Bracchi Ricard V, Fischer R, Owens E, Ricard J, et al. Soluble TNFα Signaling within the Spinal Cord Contributes to the Development of Autonomic Dysreflexia and Ensuing Vascular and Immune Dysfunction after Spinal Cord Injury. J Neurosci. 2018;38:4146-4162 pubmed publisher

Seipold L, Altmeppen H, Koudelka T, Tholey A, Kaspárek P, Sedlacek R, et al. In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15. Cell Mol Life Sci. 2018;75:3251-3267 pubmed publisher

Rizzi C, Tiberi A, Giustizieri M, Marrone M, Gobbo F, Carucci N, et al. NGF steers microglia toward a neuroprotective phenotype. Glia. 2018;66:1395-1416 pubmed publisher

Casali B, Reed Geaghan E, Landreth G. Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer's disease. J Neuroinflammation. 2018;15:43 pubmed publisher

Niraula A, Wang Y, Godbout J, Sheridan J. Corticosterone Production during Repeated Social Defeat Causes Monocyte Mobilization from the Bone Marrow, Glucocorticoid Resistance, and Neurovascular Adhesion Molecule Expression. J Neurosci. 2018;38:2328-2340 pubmed publisher

Watanabe S, Komine O, Endo F, Wakasugi K, Yamanaka K. Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice. J Neurochem. 2018;145:80-89 pubmed publisher

Thion M, Low D, Silvin A, Chen J, Grisel P, Schulte Schrepping J, et al. Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner. Cell. 2018;172:500-516.e16 pubmed publisher

Ziegler Waldkirch S, d Errico P, Sauer J, Erny D, Savanthrapadian S, Loreth D, et al. Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease. EMBO J. 2018;37:167-182 pubmed publisher

Gasparotto J, Girardi C, Somensi N, Ribeiro C, Moreira J, Michels M, et al. Receptor for advanced glycation end products mediates sepsis-triggered amyloid-β accumulation, Tau phosphorylation, and cognitive impairment. J Biol Chem. 2018;293:226-244 pubmed publisher

Jiang Y, Lin X, Tang Z, Lee C, Tian G, Du Y, et al. Critical role of caveolin-1 in ocular neovascularization and multitargeted antiangiogenic effects of cavtratin via JNK. Proc Natl Acad Sci U S A. 2017;114:10737-10742 pubmed publisher

Salazar S, Gallardo C, Kaufman A, Herber C, Haas L, Robinson S, et al. Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease. J Neurosci. 2017;37:9207-9221 pubmed publisher

Bialas A, Presumey J, Das A, van der Poel C, Lapchak P, Mesin L, et al. Microglia-dependent synapse loss in type I interferon-mediated lupus. Nature. 2017;546:539-543 pubmed publisher

DeWalt G, Eldred W. Visual system pathology in humans and animal models of blast injury. J Comp Neurol. 2017;525:2955-2967 pubmed publisher

Gosselin D, Skola D, Coufal N, Holtman I, Schlachetzki J, Sajti E, et al. An environment-dependent transcriptional network specifies human microglia identity. Science. 2017;356: pubmed publisher

Barazzuol L, Ju L, Jeggo P. A coordinated DNA damage response promotes adult quiescent neural stem cell activation. PLoS Biol. 2017;15:e2001264 pubmed publisher

Castellano J, Mosher K, Abbey R, McBride A, James M, Berdnik D, et al. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature. 2017;544:488-492 pubmed publisher

Schludi M, Becker L, Garrett L, Gendron T, Zhou Q, Schreiber F, et al. Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss. Acta Neuropathol. 2017;134:241-254 pubmed publisher

Vaughn A, Cooper E, DiLorenzo P, O Loughlin L, Konkel M, Peters J, et al. Energy-dense diet triggers changes in gut microbiota, reorganization of gut?brain vagal communication and increases body fat accumulation. Acta Neurobiol Exp (Wars). 2017;77:18-30 pubmed

Rong H, Zhao Z, Feng J, Lei Y, Wu H, Sun R, et al. The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. Brain Behav Immun. 2017;64:195-207 pubmed publisher

Hauptmann M, Burkhardt N, Munderloh U, Kuehl S, Richardt U, Krasemann S, et al. GFPuv-Expressing Recombinant Rickettsia typhi: a Useful Tool for the Study of Pathogenesis and CD8+ T Cell Immunology in R. typhi Infection. Infect Immun. 2017;85: pubmed publisher

Fonseca M, Chu S, Hernandez M, Fang M, Modarresi L, Selvan P, et al. Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain. J Neuroinflammation. 2017;14:48 pubmed publisher

Bucks S, Cox B, Vlosich B, Manning J, Nguyen T, Stone J. Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice. elife. 2017;6: pubmed publisher

Pignataro D, Sucunza D, Vanrell L, Lopez Franco E, Dopeso Reyes I, Vales A, et al. Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System. Front Neuroanat. 2017;11:2 pubmed publisher

Aragon M, Topper L, Tyler C, Sanchez B, Zychowski K, Young T, et al. Serum-borne bioactivity caused by pulmonary multiwalled carbon nanotubes induces neuroinflammation via blood-brain barrier impairment. Proc Natl Acad Sci U S A. 2017;114:E1968-E1976 pubmed publisher

Vermillion M, Lei J, Shabi Y, Baxter V, Crilly N, McLane M, et al. Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes. Nat Commun. 2017;8:14575 pubmed publisher

Zheng T, Pu J, Chen Y, Mao Y, Guo Z, Pan H, et al. Plasma Exosomes Spread and Cluster Around ?-Amyloid Plaques in an Animal Model of Alzheimer's Disease. Front Aging Neurosci. 2017;9:12 pubmed publisher

Kuipers H, Yoon J, van Horssen J, Han M, Bollyky P, Palmer T, et al. Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination. Proc Natl Acad Sci U S A. 2017;114:E1745-E1754 pubmed publisher

Lim E, Nakanishi S, Hoghooghi V, Eaton S, Palmer A, Frederick A, et al. AlphaB-crystallin regulates remyelination after peripheral nerve injury. Proc Natl Acad Sci U S A. 2017;114:E1707-E1716 pubmed publisher

Mindos T, Dun X, North K, Doddrell R, Schulz A, Edwards P, et al. Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity. J Cell Biol. 2017;216:495-510 pubmed publisher

Zhu Y, Lyapichev K, Lee D, Motti D, Ferraro N, Zhang Y, et al. Macrophage Transcriptional Profile Identifies Lipid Catabolic Pathways That Can Be Therapeutically Targeted after Spinal Cord Injury. J Neurosci. 2017;37:2362-2376 pubmed publisher

Yip P, Carrillo Jimenez A, King P, Vilalta A, Nomura K, Chau C, et al. Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration. Sci Rep. 2017;7:41689 pubmed publisher

Stayte S, Rentsch P, Tröscher A, Bamberger M, Li K, Vissel B. Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo. PLoS ONE. 2017;12:e0167211 pubmed publisher

Berghoff S, Gerndt N, Winchenbach J, Stumpf S, Hosang L, Odoardi F, et al. Dietary cholesterol promotes repair of demyelinated lesions in the adult brain. Nat Commun. 2017;8:14241 pubmed publisher

Tufail Y, Cook D, Fourgeaud L, Powers C, Merten K, Clark C, et al. Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia. Neuron. 2017;93:574-586.e8 pubmed publisher

Kallakuri S, Desai A, Feng K, Tummala S, Saif T, Chen C, et al. Neuronal Injury and Glial Changes Are Hallmarks of Open Field Blast Exposure in Swine Frontal Lobe. PLoS ONE. 2017;12:e0169239 pubmed publisher

Zhao L, Li J, Fu Y, Zhang M, Wang B, Ouellette J, et al. Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration. J Neuroinflammation. 2017;14:14 pubmed publisher

GuhaSarkar D, Neiswender J, Su Q, Gao G, Sena Esteves M. Intracranial AAV-IFN-? gene therapy eliminates invasive xenograft glioblastoma and improves survival in orthotopic syngeneic murine model. Mol Oncol. 2017;11:180-193 pubmed publisher

Lee I, Koo K, Jung K, Kim M, Kim I, Hwang K, et al. Neurogenin-2-transduced human neural progenitor cells attenuate neonatal hypoxic-ischemic brain injury. Transl Res. 2017;183:121-136.e9 pubmed publisher

Aggarwal T, Hoeber J, Ivert P, Vasylovska S, Kozlova E. Boundary Cap Neural Crest Stem Cells Promote Survival of Mutant SOD1 Motor Neurons. Neurotherapeutics. 2017;14:773-783 pubmed publisher

Takahashi H, Klein Z, Bhagat S, Kaufman A, Kostylev M, Ikezu T, et al. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network. Acta Neuropathol. 2017;133:785-807 pubmed publisher

Rodriguez Callejas J, Fuchs E, Perez Cruz C. Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common Marmoset. Front Aging Neurosci. 2016;8:315 pubmed publisher

Guillot Sestier M, Weitz T, Town T. Quantitative 3D In Silico Modeling (q3DISM) of Cerebral Amyloid-beta Phagocytosis in Rodent Models of Alzheimer's Disease. J Vis Exp. 2016;: pubmed publisher

Hellström Erkenstam N, Smith P, Fleiss B, Nair S, Svedin P, Wang W, et al. Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury. Front Cell Neurosci. 2016;10:286 pubmed publisher

Park T, Ryu Y, Park H, Kim J, Go J, Noh J, et al. Humulus japonicus inhibits the progression of Alzheimer's disease in a APP/PS1 transgenic mouse model. Int J Mol Med. 2017;39:21-30 pubmed publisher

Jablonska B, Gierdalski M, Chew L, Hawley T, Catron M, Lichauco A, et al. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun. 2016;7:13866 pubmed publisher

Meng Z, Zhao T, Zhou K, Zhong Q, Wang Y, Xiong X, et al. A20 Ameliorates Intracerebral Hemorrhage-Induced Inflammatory Injury by Regulating TRAF6 Polyubiquitination. J Immunol. 2017;198:820-831 pubmed publisher

Schäfer N, Grosche A, Reinders J, Hauck S, Pouw R, Kuijpers T, et al. Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases. Front Immunol. 2016;7:542 pubmed

Wang A, Jensen E, Rexach J, Vinters H, Hsieh Wilson L. Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration. Proc Natl Acad Sci U S A. 2016;113:15120-15125 pubmed publisher

Wang S, Jacquemyn J, Murru S, Martinelli P, Barth E, Langer T, et al. The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying. PLoS Genet. 2016;12:e1006463 pubmed publisher

Retallack H, Di Lullo E, Arias C, Knopp K, Laurie M, Sandoval Espinosa C, et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016;113:14408-14413 pubmed

Kordower J, Goetz C, Chu Y, Halliday G, Nicholson D, Musial T, et al. Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient. Ann Neurol. 2017;81:46-57 pubmed publisher

Fraser J, Essebier A, Gronostajski R, Boden M, Wainwright B, Harvey T, et al. Cell-type-specific expression of NFIX in the developing and adult cerebellum. Brain Struct Funct. 2017;222:2251-2270 pubmed publisher

Ravà M, D Andrea A, Doni M, Kress T, Ostuni R, Bianchi V, et al. Mutual epithelium-macrophage dependency in liver carcinogenesis mediated by ST18. Hepatology. 2017;65:1708-1719 pubmed publisher

Hayano Y, Takasu K, Koyama Y, Yamada M, Ogawa K, Minami K, et al. Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B. J Exp Med. 2016;213:2949-2966 pubmed

Hübner N, Mechling A, Lee H, Reisert M, Bienert T, Hennig J, et al. The connectomics of brain demyelination: Functional and structural patterns in the cuprizone mouse model. Neuroimage. 2017;146:1-18 pubmed publisher

Xie Y, Guo H, Wang L, Xu L, Zhang X, Yu L, et al. Human albumin attenuates excessive innate immunity via inhibition of microglial Mincle/Syk signaling in subarachnoid hemorrhage. Brain Behav Immun. 2017;60:346-360 pubmed publisher

Le Blon D, Guglielmetti C, Hoornaert C, Quarta A, Daans J, Dooley D, et al. Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model. J Neuroinflammation. 2016;13:288 pubmed

Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed publisher

Cho S, Song J, Shin J, Kim S. Neonatal disease environment limits the efficacy of retinal transplantation in the LCA8 mouse model. BMC Ophthalmol. 2016;16:193 pubmed

Shepherd D, Tsai S, O Brien T, Farrer R, Kartje G. Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats. Front Neurosci. 2016;10:467 pubmed

Kirschbaum K, Sonner J, Zeller M, Deumelandt K, Bode J, Sharma R, et al. In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis. Proc Natl Acad Sci U S A. 2016;113:13227-13232 pubmed

Zhan X, Stamova B, Jin L, DeCarli C, Phinney B, Sharp F. Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology. 2016;87:2324-2332 pubmed

Goebbels S, Wieser G, Pieper A, Spitzer S, Weege B, Yan K, et al. A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination. Nat Neurosci. 2017;20:10-15 pubmed publisher

Koyanagi S, Kusunose N, Taniguchi M, Akamine T, Kanado Y, Ozono Y, et al. Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia. Nat Commun. 2016;7:13102 pubmed publisher

Alvarez Saavedra M, De Repentigny Y, Yang D, O Meara R, Yan K, Hashem L, et al. Voluntary Running Triggers VGF-Mediated Oligodendrogenesis to Prolong the Lifespan of Snf2h-Null Ataxic Mice. Cell Rep. 2016;17:862-875 pubmed publisher

He J, Xiang Z, Zhu X, Ai Z, Shen J, Huang T, et al. Neuroprotective Effects of 7, 8-dihydroxyflavone on Midbrain Dopaminergic Neurons in MPP+-treated Monkeys. Sci Rep. 2016;6:34339 pubmed publisher

Hofmann K, Lamberz C, Piotrowitz K, Offermann N, But D, Scheller A, et al. Tanycytes and a differential fatty acid metabolism in the hypothalamus. Glia. 2017;65:231-249 pubmed publisher

Pang Y, Dai X, Roller A, Carter K, Paul I, Bhatt A, et al. Early Postnatal Lipopolysaccharide Exposure Leads to Enhanced Neurogenesis and Impaired Communicative Functions in Rats. PLoS ONE. 2016;11:e0164403 pubmed publisher

Dekens D, Naudé P, Engelborghs S, Vermeiren Y, Van Dam D, Oude Voshaar R, et al. Neutrophil Gelatinase-Associated Lipocalin and its Receptors in Alzheimer's Disease (AD) Brain Regions: Differential Findings in AD with and without Depression. J Alzheimers Dis. 2017;55:763-776 pubmed

Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Koike M, Uchiyama Y, et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep. 2016;6:34575 pubmed publisher

Guglielmetti C, Le Blon D, Santermans E, Salas Perdomo A, Daans J, De Vocht N, et al. Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages. Glia. 2016;64:2181-2200 pubmed publisher

Vidigal de Castro M, Barbizan R, Seabra Ferreira R, Barraviera B, Leite Rodrigues de Oliveira A. Direct Spinal Ventral Root Repair following Avulsion: Effectiveness of a New Heterologous Fibrin Sealant on Motoneuron Survival and Regeneration. Neural Plast. 2016;2016:2932784 pubmed publisher

Draheim T, Liessem A, Scheld M, Wilms F, Weißflog M, Denecke B, et al. Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model. Glia. 2016;64:2219-2230 pubmed publisher

Wu Q, Yang X, Zhang Y, Zhang L, Feng L. Chronic mild stress accelerates the progression of Parkinson's disease in A53T ?-synuclein transgenic mice. Exp Neurol. 2016;285:61-71 pubmed publisher

Kuan W, Bennett N, He X, Skepper J, Martynyuk N, Wijeyekoon R, et al. ?-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function. Exp Neurol. 2016;285:72-81 pubmed publisher

Dadsetan S, Balzano T, Forteza J, Agusti A, Cabrera Pastor A, Taoro Gonzalez L, et al. Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. J Neuroinflammation. 2016;13:245 pubmed publisher

Balusu S, Van Wonterghem E, De Rycke R, Raemdonck K, Stremersch S, Gevaert K, et al. Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles. EMBO Mol Med. 2016;8:1162-1183 pubmed publisher

Xu H, Gelyana E, Rajsombath M, Yang T, Li S, Selkoe D. Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid ?-Protein Oligomers. J Neurosci. 2016;36:9041-56 pubmed publisher

Steffen J, Krohn M, Paarmann K, Schwitlick C, Brüning T, Marreiros R, et al. Revisiting rodent models: Octodon degus as Alzheimer's disease model?. Acta Neuropathol Commun. 2016;4:91 pubmed publisher

Vermeij W, Dollé M, Reiling E, Jaarsma D, Payan Gomez C, Bombardieri C, et al. Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice. Nature. 2016;537:427-431 pubmed publisher

Bombeiro A, Thomé R, Oliveira Nunes S, Monteiro Moreira B, Verinaud L, Oliveira A. MHC-I and PirB Upregulation in the Central and Peripheral Nervous System following Sciatic Nerve Injury. PLoS ONE. 2016;11:e0161463 pubmed publisher

Papp S, Moderzynski K, Rauch J, Heine L, Kuehl S, Richardt U, et al. Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells. PLoS Negl Trop Dis. 2016;10:e0004935 pubmed publisher

Belinson H, Savage A, Fadrosh D, Kuo Y, Lin D, Valladares R, et al. Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. JCI Insight. 2016;1: pubmed publisher

Gaudet A, Mandrekar Colucci S, Hall J, Sweet D, Schmitt P, Xu X, et al. miR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair. J Neurosci. 2016;36:8516-32 pubmed publisher

McAteer K, Corrigan F, Thornton E, Turner R, Vink R. Short and Long Term Behavioral and Pathological Changes in a Novel Rodent Model of Repetitive Mild Traumatic Brain Injury. PLoS ONE. 2016;11:e0160220 pubmed publisher

Vingill S, Brockelt D, Lancelin C, Tatenhorst L, Dontcheva G, Preisinger C, et al. Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice. EMBO J. 2016;35:2008-25 pubmed publisher

Saggu R, Schumacher T, Gerich F, Rakers C, Tai K, Delekate A, et al. Astroglial NF-kB contributes to white matter damage and cognitive impairment in a mouse model of vascular dementia. Acta Neuropathol Commun. 2016;4:76 pubmed publisher

Portillo J, Lopez Corcino Y, Miao Y, Tang J, Sheibani N, Kern T, et al. CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy. Diabetes. 2017;66:483-493 pubmed publisher

Palibrk V, Suganthan R, Scheffler K, Wang W, Bjørås M, Bøe S. PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic-ischemic encephalopathy model. Cell Death Dis. 2016;7:e2320 pubmed publisher

Alves S, Marais T, Biferi M, Furling D, Marinello M, El Hachimi K, et al. Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins. Mol Neurodegener. 2016;11:58 pubmed publisher

Kawahara K, Hirata H, Ohbuchi K, Nishi K, Maeda A, Kuniyasu A, et al. The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain. Glia. 2016;64:1938-61 pubmed publisher

Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H. Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system. Sci Rep. 2016;6:30006 pubmed publisher

Sato M, Kawano M, Yanagawa Y, Hayashi Y. In vivo two-photon imaging of striatal neuronal circuits in mice. Neurobiol Learn Mem. 2016;135:146-151 pubmed publisher

Miloudi K, Binet F, Wilson A, Cerani A, Oubaha M, Ménard C, et al. Truncated netrin-1 contributes to pathological vascular permeability in diabetic retinopathy. J Clin Invest. 2016;126:3006-22 pubmed publisher

Duggett N, Griffiths L, McKenna O, De Santis V, Yongsanguanchai N, Mokori E, et al. Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy. Neuroscience. 2016;333:13-26 pubmed publisher

Bombeiro A, Santini J, Thomé R, Ferreira E, Nunes S, Moreira B, et al. Enhanced Immune Response in Immunodeficient Mice Improves Peripheral Nerve Regeneration Following Axotomy. Front Cell Neurosci. 2016;10:151 pubmed publisher

Neves J, Zhu J, Sousa Victor P, Konjikusic M, Riley R, Chew S, et al. Immune modulation by MANF promotes tissue repair and regenerative success in the retina. Science. 2016;353:aaf3646 pubmed publisher

Sommer A, Fadler T, Dorfmeister E, Hoffmann A, Xiang W, Winner B, et al. Infiltrating T lymphocytes reduce myeloid phagocytosis activity in synucleinopathy model. J Neuroinflammation. 2016;13:174 pubmed publisher

Vasek M, Garber C, Dorsey D, Durrant D, Bollman B, Soung A, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016;534:538-43 pubmed publisher

Tam W, Au N, Ma C. The association between laminin and microglial morphology in vitro. Sci Rep. 2016;6:28580 pubmed publisher

Ure K, Lu H, Wang W, Ito Ishida A, Wu Z, He L, et al. Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome. elife. 2016;5: pubmed publisher

Hutchinson E, Schwerin S, Radomski K, Irfanoglu M, Juliano S, Pierpaoli C. Quantitative MRI and DTI Abnormalities During the Acute Period Following CCI in the Ferret. Shock. 2016;46:167-76 pubmed publisher

Safaiyan S, Kannaiyan N, Snaidero N, Brioschi S, Biber K, Yona S, et al. Age-related myelin degradation burdens the clearance function of microglia during aging. Nat Neurosci. 2016;19:995-8 pubmed publisher

Sawada Y, Konno A, Nagaoka J, Hirai H. Inflammation-induced reversible switch of the neuron-specific enolase promoter from Purkinje neurons to Bergmann glia. Sci Rep. 2016;6:27758 pubmed publisher

Kim H, Lee J, Park K, Kim W, Roh G. A mitochondrial division inhibitor, Mdivi-1, inhibits mitochondrial fragmentation and attenuates kainic acid-induced hippocampal cell death. BMC Neurosci. 2016;17:33 pubmed publisher

Huang R, Harmsen S, Samii J, Karabeber H, Pitter K, Holland E, et al. High Precision Imaging of Microscopic Spread of Glioblastoma with a Targeted Ultrasensitive SERRS Molecular Imaging Probe. Theranostics. 2016;6:1075-84 pubmed publisher

Morisaki Y, Niikura M, Watanabe M, Onishi K, Tanabe S, Moriwaki Y, et al. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Sci Rep. 2016;6:27354 pubmed publisher

Hayashi Y, Morinaga S, Zhang J, Satoh Y, Meredith A, Nakata T, et al. BK channels in microglia are required for morphine-induced hyperalgesia. Nat Commun. 2016;7:11697 pubmed publisher

Nagaoka A, Takehara H, Hayashi Takagi A, Noguchi J, Ishii K, Shirai F, et al. Abnormal intrinsic dynamics of dendritic spines in a fragile X syndrome mouse model in vivo. Sci Rep. 2016;6:26651 pubmed publisher

Lim S, Hosaka K, Nakamura M, Cao Y. Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis. Oncotarget. 2016;7:38282-38291 pubmed publisher

Ricard C, Tchoghandjian A, Luche H, Grenot P, Figarella Branger D, Rougon G, et al. Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice. Sci Rep. 2016;6:26381 pubmed publisher

Marignier R, Ruiz A, Cavagna S, Nicole A, Watrin C, Touret M, et al. Neuromyelitis optica study model based on chronic infusion of autoantibodies in rat cerebrospinal fluid. J Neuroinflammation. 2016;13:111 pubmed publisher

Wharton K, Quigley C, Themeles M, Dunstan R, Doyle K, Cahir McFarland E, et al. JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection. PLoS ONE. 2016;11:e0155897 pubmed publisher

Finnie J, Blumbergs P, Manavis J. Temporal Sequence of Autolysis in the Cerebellar Cortex of the Mouse. J Comp Pathol. 2016;154:323-8 pubmed publisher

Tamagawa T, Shinoda M, Honda K, Furukawa A, Kaji K, Nagashima H, et al. Involvement of Microglial P2Y12 Signaling in Tongue Cancer Pain. J Dent Res. 2016;95:1176-82 pubmed publisher

Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. Nat Commun. 2016;7:11385 pubmed publisher

Mohr M, Garcia F, Doncarlos L, Sisk C. Neurons and Glial Cells Are Added to the Female Rat Anteroventral Periventricular Nucleus During Puberty. Endocrinology. 2016;157:2393-402 pubmed publisher

Szalay G, Martinecz B, Lénárt N, Kornyei Z, Orsolits B, Judák L, et al. Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke. Nat Commun. 2016;7:11499 pubmed publisher

Tong H, Kang W, Davy P, Shi Y, Sun S, Allsopp R, et al. Monocyte Trafficking, Engraftment, and Delivery of Nanoparticles and an Exogenous Gene into the Acutely Inflamed Brain Tissue - Evaluations on Monocyte-Based Delivery System for the Central Nervous System. PLoS ONE. 2016;11:e0154022 pubmed publisher

Anesten F, Holt M, Schéle E, Pálsdóttir V, Reimann F, Gribble F, et al. Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca2+ influx in response to IL-6. Am J Physiol Regul Integr Comp Physiol. 2016;311:R115-23 pubmed publisher

Bouvier D, Jones E, Quesseveur G, Davoli M, A Ferreira T, Quirion R, et al. High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease. Sci Rep. 2016;6:24544 pubmed publisher

Brüggen B, Kremser C, Bickert A, Ebel P, Vom Dorp K, Schultz K, et al. Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea. Eur J Neurosci. 2016;44:1700-13 pubmed publisher

Chtarto A, Humbert Claude M, Bockstael O, Das A, Boutry S, Breger L, et al. A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses. Mol Ther Methods Clin Dev. 2016;5:16027 pubmed publisher

Kim S, Hayashi H, Ishikawa T, Shibata K, Shigetomi E, Shinozaki Y, et al. Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain. J Clin Invest. 2016;126:1983-97 pubmed publisher

Fourgeaud L, Traves P, Tufail Y, Leal Bailey H, Lew E, Burrola P, et al. TAM receptors regulate multiple features of microglial physiology. Nature. 2016;532:240-244 pubmed publisher

Hong S, Beja Glasser V, Nfonoyim B, Frouin A, Li S, Ramakrishnan S, et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science. 2016;352:712-716 pubmed publisher

Viringipurampeer I, Metcalfe A, Bashar A, Sivak O, Yanai A, Mohammadi Z, et al. NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration. Hum Mol Genet. 2016;25:1501-16 pubmed publisher

Monai H, Ohkura M, Tanaka M, Oe Y, Konno A, Hirai H, et al. Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain. Nat Commun. 2016;7:11100 pubmed publisher

Anastasiadou S, Knöll B. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 2016;279:243-260 pubmed publisher

Osterloh A, Papp S, Moderzynski K, Kuehl S, Richardt U, Fleischer B. Persisting Rickettsia typhi Causes Fatal Central Nervous System Inflammation. Infect Immun. 2016;84:1615-1632 pubmed publisher

McFarland B, Marks M, Rowse A, Fehling S, Gerigk M, Qin H, et al. Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma. Oncotarget. 2016;7:20621-35 pubmed publisher

Jennewein L, Ronellenfitsch M, Antonietti P, Ilina E, Jung J, Stadel D, et al. Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas. Oncotarget. 2016;7:20016-32 pubmed publisher

Zhao C, Deng Y, Liu L, Yu K, Zhang L, Wang H, et al. Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nat Commun. 2016;7:10883 pubmed publisher

Sipe G, Lowery R, Tremblay M, Kelly E, Lamantia C, Majewska A. Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex. Nat Commun. 2016;7:10905 pubmed publisher

Recordati C, De Maglie M, Bianchessi S, Argentiere S, Cella C, Mattiello S, et al. Tissue distribution and acute toxicity of silver after single intravenous administration in mice: nano-specific and size-dependent effects. Part Fibre Toxicol. 2016;13:12 pubmed publisher

Liu H, Garzoni L, Herry C, Durosier L, Cao M, Burns P, et al. Can Monitoring Fetal Intestinal Inflammation Using Heart Rate Variability Analysis Signal Incipient Necrotizing Enterocolitis of the Neonate?. Pediatr Crit Care Med. 2016;17:e165-76 pubmed publisher

Fonseca M, Chu S, Pierce A, Brubaker W, Hauhart R, Mastroeni D, et al. Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function. PLoS ONE. 2016;11:e0149792 pubmed publisher

Matsumoto M, Nakamachi T, Watanabe J, Sugiyama K, Ohtaki H, Murai N, et al. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke. J Mol Neurosci. 2016;59:270-9 pubmed publisher

Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf W, Grozdanov V, et al. Peripheral monocytes are functionally altered and invade the CNS in ALS patients. Acta Neuropathol. 2016;132:391-411 pubmed publisher

Polyzos A, Holt A, Brown C, Cosme C, Wipf P, Gomez Marin A, et al. Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes. Hum Mol Genet. 2016;25:1792-802 pubmed publisher

Winston C, Noël A, Neustadtl A, Parsadanian M, Barton D, Chellappa D, et al. Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma. Am J Pathol. 2016;186:552-67 pubmed publisher

Bisht K, Sharma K, Lecours C, Sánchez M, El Hajj H, Milior G, et al. Dark microglia: A new phenotype predominantly associated with pathological states. Glia. 2016;64:826-39 pubmed publisher

Furman J, Sompol P, Kraner S, Pleiss M, Putman E, Dunkerson J, et al. Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury. J Neurosci. 2016;36:1502-15 pubmed publisher

Sharma A, Lyashchenko A, Lu L, Nasrabady S, Elmaleh M, Mendelsohn M, et al. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nat Commun. 2016;7:10465 pubmed publisher

Wilhelmus M, de Jager M, Smit A, van der Loo R, Drukarch B. Catalytically active tissue transglutaminase colocalises with Aβ pathology in Alzheimer's disease mouse models. Sci Rep. 2016;6:20569 pubmed publisher

Li H, Ruberu K, Karl T, Garner B. Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions. PLoS ONE. 2016;11:e0148238 pubmed publisher

Tokuda E, Brännström T, Andersen P, Marklund S. Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase. Acta Neuropathol Commun. 2016;4:6 pubmed publisher

Lee Kubli C, Ingves M, Henry K, Shiao R, Collyer E, Tuszynski M, et al. Analysis of the behavioral, cellular and molecular characteristics of pain in severe rodent spinal cord injury. Exp Neurol. 2016;278:91-104 pubmed publisher

Matzkin M, Miquet J, Fang Y, Hill C, Turyn D, Calandra R, et al. Alterations in oxidative, inflammatory and apoptotic events in short-lived and long-lived mice testes. Aging (Albany NY). 2016;8:95-110 pubmed

Hackett A, Lee D, Dawood A, Rodriguez M, Funk L, Tsoulfas P, et al. STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury. Neurobiol Dis. 2016;89:10-22 pubmed publisher

Korwitz A, Merkwirth C, Richter Dennerlein R, Tröder S, Sprenger H, Quirós P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed publisher

Kang S, Murphy R, Hwang S, Lee S, Harburg D, Krueger N, et al. Bioresorbable silicon electronic sensors for the brain. Nature. 2016;530:71-6 pubmed publisher

Yuan P, Grutzendler J. Attenuation of β-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural Activity. J Neurosci. 2016;36:632-41 pubmed publisher

Lian H, Litvinchuk A, Chiang A, Aithmitti N, Jankowsky J, Zheng H. Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease. J Neurosci. 2016;36:577-89 pubmed publisher

Backes H, Walberer M, Ladwig A, Rueger M, Neumaier B, Endepols H, et al. Glucose consumption of inflammatory cells masks metabolic deficits in the brain. Neuroimage. 2016;128:54-62 pubmed publisher

Osman A, Neumann S, Kuhn H, Blomgren K. Caspase inhibition impaired the neural stem/progenitor cell response after cortical ischemia in mice. Oncotarget. 2016;7:2239-48 pubmed publisher

Kindy M, Yu J, Zhu H, Smith M, Gattoni Celli S. A therapeutic cancer vaccine against GL261 murine glioma. J Transl Med. 2016;14:1 pubmed publisher

Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed publisher

Slowicka K, Vereecke L, Mc Guire C, Sze M, Maelfait J, Kolpe A, et al. Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling. Eur J Immunol. 2016;46:971-80 pubmed publisher

Gilkes J, Bloom M, Heldermon C. Mucopolysaccharidosis IIIB confers enhanced neonatal intracranial transduction by AAV8 but not by 5, 9 or rh10. Gene Ther. 2016;23:263-71 pubmed publisher

Haas L, Salazar S, Kostylev M, Um J, Kaufman A, Strittmatter S. Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease. Brain. 2016;139:526-46 pubmed publisher

Traka M, Podojil J, McCarthy D, Miller S, Popko B. Oligodendrocyte death results in immune-mediated CNS demyelination. Nat Neurosci. 2016;19:65-74 pubmed publisher

Elahi M, Motoi Y, Matsumoto S, Hasan Z, Ishiguro K, Hattori N. Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice. Neurosci Lett. 2016;610:207-12 pubmed publisher

Hellwig S, Brioschi S, Dieni S, Frings L, Masuch A, Blank T, et al. Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice. Brain Behav Immun. 2016;55:126-137 pubmed publisher

Zhu J, Wang Z, Zhang N, Ma J, Xu S, Wang Y, et al. Protein Interacting C-Kinase 1 Modulates Surface Expression of P2Y6 Purinoreceptor, Actin Polymerization and Phagocytosis in Microglia. Neurochem Res. 2016;41:795-803 pubmed publisher

Sang H, Liu L, Wang L, Qiu Z, Li M, Yu L, et al. Opposite roles of bradykinin B1 and B2 receptors during cerebral ischaemia-reperfusion injury in experimental diabetic rats. Eur J Neurosci. 2016;43:53-65 pubmed publisher

Sabogal Guáqueta A, Osorio E, Cardona Gómez G. Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice. Neuropharmacology. 2016;102:111-20 pubmed publisher

Watamura N, Toba J, Yoshii A, Nikkuni M, Ohshima T. Colocalization of phosphorylated forms of WAVE1, CRMP2, and tau in Alzheimer's disease model mice: Involvement of Cdk5 phosphorylation and the effect of ATRA treatment. J Neurosci Res. 2016;94:15-26 pubmed publisher

Smolek T, Madari A, Farbáková J, Kandrac O, Jadhav S, Cente M, et al. Tau hyperphosphorylation in synaptosomes and neuroinflammation are associated with canine cognitive impairment. J Comp Neurol. 2016;524:874-95 pubmed publisher

Currais A, Farrokhi C, Dargusch R, Goujon Svrzic M, Maher P. Dietary glycemic index modulates the behavioral and biochemical abnormalities associated with autism spectrum disorder. Mol Psychiatry. 2016;21:426-36 pubmed publisher

Hubert V, Hristovska I, Karpati S, Benkeder S, Dey A, Dumot C, et al. Multimodal Imaging with NanoGd Reveals Spatiotemporal Features of Neuroinflammation after Experimental Stroke. Adv Sci (Weinh). 2021;8:e2101433 pubmed publisher

Zhang N, Lin J, Lin V, Milbreta U, Chin J, Chew E, et al. A 3D Fiber-Hydrogel Based Non-Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury. Adv Sci (Weinh). 2021;8:e2100805 pubmed publisher

Ferreira N, Gram H, Sorrentino Z, Gregersen E, Schmidt S, Reimer L, et al. Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential. Acta Neuropathol. 2021;142:87-115 pubmed publisher

Souder D, Dreischmeier I, Smith A, Wright S, Martin S, Sagar M, et al. Rhesus monkeys as a translational model for late-onset Alzheimer's disease. Aging Cell. 2021;20:e13374 pubmed publisher

Adlimoghaddam A, Odero G, Glazner G, Turner R, Albensi B. Nilotinib Improves Bioenergetic Profiling in Brain Astroglia in the 3xTg Mouse Model of Alzheimer's Disease. Aging Dis. 2021;12:441-465 pubmed publisher

van Olst L, Rodriguez Mogeda C, Picón C, Kiljan S, James R, Kamermans A, et al. Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration. Acta Neuropathol. 2021;141:881-899 pubmed publisher

Uneda A, Kurozumi K, Fujimura A, Fujii K, Ishida J, Shimazu Y, et al. Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration. Acta Neuropathol Commun. 2021;9:29 pubmed publisher

Oda W, Fujita Y, Baba K, Mochizuki H, Niwa H, Yamashita T. Inhibition of repulsive guidance molecule-a protects dopaminergic neurons in a mouse model of Parkinson's disease. Cell Death Dis. 2021;12:181 pubmed publisher

Choi Y, Dunn Meynell A, Marchese M, Blumberg B, Gaindh D, Dowling P, et al. Erythropoietin-derived peptide treatment reduced neurological deficit and neuropathological changes in a mouse model of tauopathy. Alzheimers Res Ther. 2021;13:32 pubmed publisher

Verma A, Zhu P, Xu K, Du T, Liao S, Liang Z, et al. Angiotensin-(1-7) Expressed From Lactobacillus Bacteria Protect Diabetic Retina in Mice. Transl Vis Sci Technol. 2020;9:20 pubmed publisher

Tripathi A, Thangaraj A, Chivero E, Periyasamy P, Burkovetskaya M, Niu F, et al. N-Acetylcysteine Reverses Antiretroviral-Mediated Microglial Activation by Attenuating Autophagy-Lysosomal Dysfunction. Front Neurol. 2020;11:840 pubmed publisher

Dhir A, Bruun D, Guignet M, Tsai Y, Gonzalez E, Calsbeek J, et al. Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate-induced status epilepticus in rats. Ann N Y Acad Sci. 2020;1480:183-206 pubmed publisher

Lackie R, Marques Lopes J, Ostapchenko V, Good S, Choy W, van Oosten Hawle P, et al. Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2020;8:143 pubmed publisher

Ko K, Milbrandt J, DiAntonio A. SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration. J Cell Biol. 2020;219: pubmed publisher

Sullivan G, Knutsen A, Peruzzotti Jametti L, Korotcov A, Bosomtwi A, Dardzinski B, et al. Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits. Acta Neuropathol Commun. 2020;8:84 pubmed publisher

Li T, Chiou B, Gilman C, Luo R, Koshi T, Yu D, et al. A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding. EMBO J. 2020;39:e104136 pubmed publisher

Zhang K, Rui G, Zhang J, Guo L, An G, Lin J, et al. Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke. BMC Neurosci. 2020;21:21 pubmed publisher

Llorens F, Hermann P, Villar Piqué A, Diaz Lucena D, Nagga K, Hansson O, et al. Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia. Nat Commun. 2020;11:619 pubmed publisher

Tripathi A, Thangaraj A, Chivero E, Periyasamy P, Callen S, Burkovetskaya M, et al. Antiretroviral-Mediated Microglial Activation Involves Dysregulated Autophagy and Lysosomal Dysfunction. Cells. 2019;8: pubmed publisher

Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón Sandoval J, et al. CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice. Brain. 2019;142:3243-3264 pubmed publisher

Narayan D, Ao J, Wood J, Casson R, Chidlow G. Spatio-temporal characterization of S- and M/L-cone degeneration in the Rd1 mouse model of retinitis pigmentosa. BMC Neurosci. 2019;20:46 pubmed publisher

Liu L, Kelly M, Wierzbicki E, Escober Nario I, Vollmer M, DORE S. Nrf2 Plays an Essential Role in Long-Term Brain Damage and Neuroprotection of Korean Red Ginseng in a Permanent Cerebral Ischemia Model. Antioxidants (Basel). 2019;8: pubmed publisher

Rojo R, Raper A, Ozdemir D, Lefèvre L, Grabert K, Wollscheid Lengeling E, et al. Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations. Nat Commun. 2019;10:3215 pubmed publisher

Pascual García M, Bonfill Teixidor E, Planas Rigol E, Rubio Perez C, Iurlaro R, Arias A, et al. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy. Nat Commun. 2019;10:2416 pubmed publisher

Harada Y, Zhang J, Imari K, Yamasaki R, Ni J, Wu Z, et al. Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis. Pain. 2019;: pubmed publisher

Smith A, Duan T, Verkman A. Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer's disease by remodeling peri-plaque astrocyte structure. Acta Neuropathol Commun. 2019;7:74 pubmed publisher

Murru S, Hess S, Barth E, Almajan E, Schatton D, Hermans S, et al. Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019;67:1526-1541 pubmed publisher

Salamanca L, Mechawar N, Murai K, Balling R, Bouvier D, Skupin A. MIC-MAC: An automated pipeline for high-throughput characterization and classification of three-dimensional microglia morphologies in mouse and human postmortem brain samples. Glia. 2019;67:1496-1509 pubmed publisher

Bergner C, van der Meer F, Winkler A, Wrzos C, Türkmen M, Valizada E, et al. Microglia damage precedes major myelin breakdown in X-linked adrenoleukodystrophy and metachromatic leukodystrophy. Glia. 2019;67:1196-1209 pubmed publisher

Freitas Andrade M, Wang N, Bechberger J, De Bock M, Lampe P, Leybaert L, et al. Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke. J Exp Med. 2019;: pubmed publisher

Wimmer I, Scharler C, Zrzavy T, Kadowaki T, Mödlagl V, Rojc K, et al. Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis. Acta Neuropathol Commun. 2019;7:14 pubmed publisher

Nguyen L, Mahadeo T, Bordey A. mTOR Hyperactivity Levels Influence the Severity of Epilepsy and Associated Neuropathology in an Experimental Model of Tuberous Sclerosis Complex and Focal Cortical Dysplasia. J Neurosci. 2019;39:2762-2773 pubmed publisher

Sawicki C, Kim J, Weber M, Faw T, McKim D, Madalena K, et al. Microglia Promote Increased Pain Behavior through Enhanced Inflammation in the Spinal Cord during Repeated Social Defeat Stress. J Neurosci. 2019;39:1139-1149 pubmed publisher

Eisemann T, Costa B, Harter P, Wick W, Mittelbronn M, Angel P, et al. Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma. Neuro Oncol. 2019;21:326-336 pubmed publisher

Lee J, Nam H, Kim L, Jeon Y, Min H, Ha S, et al. TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia. Autophagy. 2018;: pubmed publisher

García Domínguez I, Veselá K, García Revilla J, Carrillo Jimenez A, Roca Ceballos M, Santiago M, et al. Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson's Disease. Front Cell Neurosci. 2018;12:398 pubmed publisher

McWilliams T, Barini E, Pohjolan Pirhonen R, Brooks S, Singh F, Burel S, et al. Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biol. 2018;8: pubmed publisher

Ceyzériat K, Ben Haim L, Denizot A, Pommier D, Matos M, Guillemaud O, et al. Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease. Acta Neuropathol Commun. 2018;6:104 pubmed publisher

Su J, Huang P, Qin M, Lu Q, Sang X, Cai Y, et al. Reduction of HIP2 expression causes motor function impairment and increased vulnerability to dopaminergic degeneration in Parkinson's disease models. Cell Death Dis. 2018;9:1020 pubmed publisher

Liu Y, Sorce S, Nuvolone M, Domange J, Aguzzi A. Lymphocyte activation gene 3 (Lag3) expression is increased in prion infections but does not modify disease progression. Sci Rep. 2018;8:14600 pubmed publisher

Nair R, Koivisto H, Jokivarsi K, Miinalainen I, Autio K, Manninen A, et al. Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice. J Neurosci. 2018;38:9781-9800 pubmed publisher

Saunders J, Hore Z, Gentry C, McMahon S, Denk F. Negative Evidence for a Functional Role of Neuronal DNMT3a in Persistent Pain. Front Mol Neurosci. 2018;11:332 pubmed publisher

Lainez N, Jonak C, Nair M, Ethell I, Wilson E, Carson M, et al. Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice. Front Immunol. 2018;9:1992 pubmed publisher

Flores J, Noël A, Foveau B, Lynham J, Lecrux C, LeBlanc A. Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer's disease mouse model. Nat Commun. 2018;9:3916 pubmed publisher

Bussian T, Aziz A, Meyer C, Swenson B, van Deursen J, Baker D. Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline. Nature. 2018;562:578-582 pubmed publisher

Andrés Benito P, Dominguez R, Colomina M, Llorens F, Povedano M, Ferrer I. YKL40 in sporadic amyotrophic lateral sclerosis: cerebrospinal fluid levels as a prognosis marker of disease progression. Aging (Albany NY). 2018;10:2367-2382 pubmed publisher

Nestor J, Arinuma Y, Huerta T, Kowal C, Nasiri E, Kello N, et al. Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitors. J Exp Med. 2018;215:2554-2566 pubmed publisher

Tay T, Sagar -, Dautzenberg J, Grün D, Prinz M. Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration. Acta Neuropathol Commun. 2018;6:87 pubmed publisher

Xiong C, Liu J, Lin D, Zhang J, Terrando N, Wu A. Complement activation contributes to perioperative neurocognitive disorders in mice. J Neuroinflammation. 2018;15:254 pubmed publisher

Chakrabarty P, Li A, Ladd T, Strickland M, Koller E, Burgess J, et al. TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. J Exp Med. 2018;215:2247-2264 pubmed publisher

Koenis D, Medzikovic L, Vos M, Beldman T, van Loenen P, Van Tiel C, et al. Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans. J Biol Chem. 2018;293:15070-15083 pubmed publisher

Liu C, Zhang C, Lo S, Ang S, Chew K, Yu D, et al. S-Nitrosylation of Divalent Metal Transporter 1 Enhances Iron Uptake to Mediate Loss of Dopaminergic Neurons and Motoric Deficit. J Neurosci. 2018;38:8364-8377 pubmed publisher

Mousseau M, Burma N, Lee K, Leduc Pessah H, Kwok C, Reid A, et al. Microglial pannexin-1 channel activation is a spinal determinant of joint pain. Sci Adv. 2018;4:eaas9846 pubmed publisher

Pedragosa J, Salas Perdomo A, Gallizioli M, Cugota R, Miro Mur F, Briansó F, et al. CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage. Acta Neuropathol Commun. 2018;6:76 pubmed publisher

Natoli R, Mason E, Jiao H, Chuah A, Patel H, Fernando N, et al. Dynamic Interplay of Innate and Adaptive Immunity During Sterile Retinal Inflammation: Insights From the Transcriptome. Front Immunol. 2018;9:1666 pubmed publisher

Welliver R, Polanco J, Seidman R, Sinha A, O Bara M, Khaku Z, et al. Muscarinic Receptor M3R Signaling Prevents Efficient Remyelination by Human and Mouse Oligodendrocyte Progenitor Cells. J Neurosci. 2018;38:6921-6932 pubmed publisher

Caprariello A, Rogers J, Morgan M, Hoghooghi V, Plemel J, Koebel A, et al. Biochemically altered myelin triggers autoimmune demyelination. Proc Natl Acad Sci U S A. 2018;115:5528-5533 pubmed publisher

Mouton Liger F, Rosazza T, Sepulveda Diaz J, Ieang A, Hassoun S, Claire E, et al. Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop. Glia. 2018;: pubmed publisher

Fröhlich D, Suchowerska A, Voss C, He R, Wolvetang E, von Jonquieres G, et al. Expression Pattern of the Aspartyl-tRNA Synthetase DARS in the Human Brain. Front Mol Neurosci. 2018;11:81 pubmed publisher

Yan S, Tu Z, Liu Z, Fan N, Yang H, Yang S, et al. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. Cell. 2018;173:989-1002.e13 pubmed publisher

Martin N, Molnar V, Szilagyi G, Elkjaer M, Nawrocki A, Okarmus J, et al. Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice. Front Immunol. 2018;9:490 pubmed publisher

Jung J, Eggleton P, Robinson A, Wang J, Gutowski N, Holley J, et al. Calnexin is necessary for T cell transmigration into the central nervous system. JCI Insight. 2018;3: pubmed publisher

Barben M, Schori C, Samardzija M, Grimm C. Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia. Mol Neurodegener. 2018;13:12 pubmed publisher

Huang Y, Xu Z, Xiong S, Qin G, Sun F, Yang J, et al. Dual extra-retinal origins of microglia in the model of retinal microglia repopulation. Cell Discov. 2018;4:9 pubmed publisher

Perkins A, Piazza M, Deak T. Stereological Analysis of Microglia in Aged Male and Female Fischer 344 Rats in Socially Relevant Brain Regions. Neuroscience. 2018;377:40-52 pubmed publisher

Hui C, St Pierre A, El Hajj H, Remy Y, Hébert S, Luheshi G, et al. Prenatal Immune Challenge in Mice Leads to Partly Sex-Dependent Behavioral, Microglial, and Molecular Abnormalities Associated with Schizophrenia. Front Mol Neurosci. 2018;11:13 pubmed publisher

Boza Serrano A, Yang Y, Paulus A, Deierborg T. Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer's disease mouse model 5xFAD. Sci Rep. 2018;8:1550 pubmed publisher

Ganesan P, Chandwani M, Creisher P, Bohn L, O Donnell L. The neonatal anti-viral response fails to control measles virus spread in neurons despite interferon-gamma expression and a Th1-like cytokine profile. J Neuroimmunol. 2018;316:80-97 pubmed publisher

McWilliams T, Prescott A, Montava Garriga L, Ball G, Singh F, Barini E, et al. Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand. Cell Metab. 2018;27:439-449.e5 pubmed publisher

Carreras I, Aytan N, Mellott T, Choi J, Lehar M, Crabtree L, et al. Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease. Brain Res. 2018;1681:34-43 pubmed publisher

Janova H, Arinrad S, Balmuth E, Mitjans M, Hertel J, Habes M, et al. Microglia ablation alleviates myelin-associated catatonic signs in mice. J Clin Invest. 2018;128:734-745 pubmed publisher

McClendon E, Shaver D, Degener O Brien K, Gong X, Nguyen T, Hoerder Suabedissen A, et al. Transient Hypoxemia Chronically Disrupts Maturation of Preterm Fetal Ovine Subplate Neuron Arborization and Activity. J Neurosci. 2017;37:11912-11929 pubmed publisher

Shen Y, Kapfhamer D, Minnella A, Kim J, Won S, Chen Y, et al. Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP. Nat Commun. 2017;8:624 pubmed publisher

Mass E, Jacome Galarza C, Blank T, Lazarov T, Durham B, Ozkaya N, et al. A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease. Nature. 2017;549:389-393 pubmed publisher

Gaudier Diaz M, Zhang N, Haines A, Surbhi -, Zhou M, Devries A. Social interaction modulates the neuroinflammatory response to global cerebral ischemia in male mice. Brain Res. 2017;1673:86-94 pubmed publisher

Chang M, Srinivasan K, Friedman B, Suto E, Modrusan Z, Lee W, et al. Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation. J Exp Med. 2017;214:2611-2628 pubmed publisher

Réu P, Khosravi A, Bernard S, Mold J, Salehpour M, Alkass K, et al. The Lifespan and Turnover of Microglia in the Human Brain. Cell Rep. 2017;20:779-784 pubmed publisher

Stein L, Zorumski C, Izumi Y. Hippocampal slice preparation in rats acutely suppresses immunoreactivity of microtubule-associated protein (Map2) and glycogen levels without affecting numbers of glia or levels of the glutamate transporter VGlut1. Brain Behav. 2017;7:e00736 pubmed publisher

McLane L, Bourne J, Evangelou A, Khandker L, Macklin W, Wood T. Loss of Tuberous Sclerosis Complex1 in Adult Oligodendrocyte Progenitor Cells Enhances Axon Remyelination and Increases Myelin Thickness after a Focal Demyelination. J Neurosci. 2017;37:7534-7546 pubmed publisher

Riera C, Tsaousidou E, Halloran J, Follett P, Hahn O, Pereira M, et al. The Sense of Smell Impacts Metabolic Health and Obesity. Cell Metab. 2017;26:198-211.e5 pubmed publisher

Delenclos M, Faroqi A, Yue M, Kurti A, Castanedes Casey M, Rousseau L, et al. Neonatal AAV delivery of alpha-synuclein induces pathology in the adult mouse brain. Acta Neuropathol Commun. 2017;5:51 pubmed publisher

Stewart A, Matyas J, Welchko R, Goldsmith A, Zeiler S, Hochgeschwender U, et al. SDF-1 overexpression by mesenchymal stem cells enhances GAP-43-positive axonal growth following spinal cord injury. Restor Neurol Neurosci. 2017;35:395-411 pubmed publisher

Grossman N, Bono D, Dedic N, Kodandaramaiah S, Rudenko A, Suk H, et al. Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields. Cell. 2017;169:1029-1041.e16 pubmed publisher

Bellesi M, de Vivo L, Chini M, Gilli F, Tononi G, Cirelli C. Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex. J Neurosci. 2017;37:5263-5273 pubmed publisher

Paci P, Gabriele S, Ris L. A new method allowing long-term potentiation recordings in hippocampal organotypic slices. Brain Behav. 2017;7:e00692 pubmed publisher

Periyasamy P, Liao K, Kook Y, Niu F, Callen S, Guo M, et al. Cocaine-Mediated Downregulation of miR-124 Activates Microglia by Targeting KLF4 and TLR4 Signaling. Mol Neurobiol. 2018;55:3196-3210 pubmed publisher

Sun Y, Lin Z, Liu C, Gong Y, Liegl R, Fredrick T, et al. Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos. J Exp Med. 2017;214:1753-1767 pubmed publisher

Hastings A, Yockey L, Jagger B, Hwang J, Uraki R, Gaitsch H, et al. TAM Receptors Are Not Required for Zika Virus Infection in Mice. Cell Rep. 2017;19:558-568 pubmed publisher

Karamita M, Barnum C, Mobius W, TANSEY M, Szymkowski D, Lassmann H, et al. Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia. JCI Insight. 2017;2: pubmed publisher

Noristani H, Gerber Y, Sabourin J, Le Corre M, Lonjon N, Mestre Frances N, et al. RNA-Seq Analysis of Microglia Reveals Time-Dependent Activation of Specific Genetic Programs following Spinal Cord Injury. Front Mol Neurosci. 2017;10:90 pubmed publisher

Schampel A, Volovitch O, Koeniger T, Scholz C, Jörg S, Linker R, et al. Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis. Proc Natl Acad Sci U S A. 2017;114:E3295-E3304 pubmed publisher

Patel S, Cox D, Gollihue J, Bailey W, Geldenhuys W, Gensel J, et al. Pioglitazone treatment following spinal cord injury maintains acute mitochondrial integrity and increases chronic tissue sparing and functional recovery. Exp Neurol. 2017;293:74-82 pubmed publisher

Dong E, Bachleda A, Xiong Y, Osawa S, Weiss E. Reduced phosphoCREB in Müller glia during retinal degeneration in rd10 mice. Mol Vis. 2017;23:90-102 pubmed

Di Pierdomenico J, García Ayuso D, Pinilla I, Cuenca N, Vidal Sanz M, Agudo Barriuso M, et al. Early Events in Retinal Degeneration Caused by Rhodopsin Mutation or Pigment Epithelium Malfunction: Differences and Similarities. Front Neuroanat. 2017;11:14 pubmed publisher

Brancaccio M, Patton A, Chesham J, Maywood E, Hastings M. Astrocytes Control Circadian Timekeeping in the Suprachiasmatic Nucleus via Glutamatergic Signaling. Neuron. 2017;93:1420-1435.e5 pubmed publisher

Bento Torres J, Sobral L, Reis R, de Oliveira R, Anthony D, Vasconcelos P, et al. Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes. Oxid Med Cell Longev. 2017;2017:4504925 pubmed publisher

Leaw B, Zhu D, Tan J, Muljadi R, Saad M, Mockler J, et al. Human amnion epithelial cells rescue cell death via immunomodulation of microglia in a mouse model of perinatal brain injury. Stem Cell Res Ther. 2017;8:46 pubmed publisher

Luo F, Herrup K, Qi X, Yang Y. Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis. Exp Neurol. 2017;292:21-34 pubmed publisher

Kota D, Prabhakara K, Toledano Furman N, Bhattarai D, Chen Q, Dicarlo B, et al. Prostaglandin E2 Indicates Therapeutic Efficacy of Mesenchymal Stem Cells in Experimental Traumatic Brain Injury. Stem Cells. 2017;35:1416-1430 pubmed publisher

Dorfman M, Krull J, Douglass J, Fasnacht R, Lara Lince F, Meek T, et al. Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice. Nat Commun. 2017;8:14556 pubmed publisher

Kraft A, Jubal E, von Laer R, Döring C, Rocha A, Grebbin M, et al. Astrocytic Calcium Waves Signal Brain Injury to Neural Stem and Progenitor Cells. Stem Cell Reports. 2017;8:701-714 pubmed publisher

Woodward N, Pakbin P, Saffari A, Shirmohammadi F, Haghani A, Sioutas C, et al. Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons. Neurobiol Aging. 2017;53:48-58 pubmed publisher

Kopec A, Rivera P, Lacagnina M, Hanamsagar R, Bilbo S. Optimized solubilization of TRIzol-precipitated protein permits Western blotting analysis to maximize data available from brain tissue. J Neurosci Methods. 2017;280:64-76 pubmed publisher

Espitia Pinzon N, Sanz Morello B, Brevé J, Bol J, Drukarch B, Bauer J, et al. Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination. Sci Rep. 2017;7:40995 pubmed publisher

Teles Grilo Ruivo L, Baker K, Conway M, Kinsley P, Gilmour G, Phillips K, et al. Coordinated Acetylcholine Release in Prefrontal Cortex and Hippocampus Is Associated with Arousal and Reward on Distinct Timescales. Cell Rep. 2017;18:905-917 pubmed publisher

Cave C, Park S, Rodriguez M, Nakamura M, Hoke A, Pletnikov M, et al. GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord. Mol Neurodegener. 2017;12:8 pubmed publisher

Ardestani P, Evans A, Yi B, Nguyen T, Coutellier L, Shamloo M. Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer's disease using a biased and selective beta-1 adrenergic receptor partial agonist. Neuropharmacology. 2017;116:371-386 pubmed publisher

Shen Y, Qin H, Chen J, Mou L, He Y, Yan Y, et al. Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons. J Cell Biol. 2016;215:719-734 pubmed

Ljungberg L, Lang Ouellette D, Yang A, Jayabal S, Quilez S, Watt A. Transient Developmental Purkinje Cell Axonal Torpedoes in Healthy and Ataxic Mouse Cerebellum. Front Cell Neurosci. 2016;10:248 pubmed

Chrobok N, Jaouën A, Fenrich K, Bol J, Wilhelmus M, Drukarch B, et al. Monocyte behaviour and tissue transglutaminase expression during experimental autoimmune encephalomyelitis in transgenic CX3CR1gfp/gfp mice. Amino Acids. 2017;49:643-658 pubmed publisher

Rodríguez C, Sobrino T, Agulla J, Bobo Jiménez V, Ramos Araque M, Duarte J, et al. Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism. Cell Death Differ. 2017;24:144-154 pubmed publisher

Wächter C, Eiden L, Naumann N, Depboylu C, Weihe E. Loss of cerebellar neurons in the progression of lentiviral disease: effects of CNS-permeant antiretroviral therapy. J Neuroinflammation. 2016;13:272 pubmed

Huang W, Abraham R, Shim B, Choe H, Page D. Zika virus infection during the period of maximal brain growth causes microcephaly and corticospinal neuron apoptosis in wild type mice. Sci Rep. 2016;6:34793 pubmed publisher

Hamzei Taj S, Kho W, Aswendt M, Collmann F, Green C, Adamczak J, et al. Dynamic Modulation of Microglia/Macrophage Polarization by miR-124 after Focal Cerebral Ischemia. J Neuroimmune Pharmacol. 2016;11:733-748 pubmed

Shi D, Shi G, Xie J, Du X, Yang H. MicroRNA-27a Inhibits Cell Migration and Invasion of Fibroblast-Like Synoviocytes by Targeting Follistatin-Like Protein 1 in Rheumatoid Arthritis. Mol Cells. 2016;39:611-8 pubmed publisher

Horlad H, Ohnishi K, Ma C, Fujiwara Y, Niino D, Ohshima K, et al. TIM-3 expression in lymphoma cells predicts chemoresistance in patients with adult T-cell leukemia/lymphoma. Oncol Lett. 2016;12:1519-1524 pubmed

Baufeld C, Osterloh A, Prokop S, Miller K, Heppner F. High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia. Acta Neuropathol. 2016;132:361-75 pubmed publisher

Zabel M, Zhao L, Zhang Y, Gonzalez S, Ma W, Wang X, et al. Microglial phagocytosis and activation underlying photoreceptor degeneration is regulated by CX3CL1-CX3CR1 signaling in a mouse model of retinitis pigmentosa. Glia. 2016;64:1479-91 pubmed publisher

He X, Lan Y, Zhang Q, Liu D, Wang Q, Liang F, et al. Deferoxamine inhibits microglial activation, attenuates blood-brain barrier disruption, rescues dendritic damage, and improves spatial memory in a mouse model of microhemorrhages. J Neurochem. 2016;138:436-47 pubmed publisher

Bolz M, Ruggli N, Borel N, Pluschke G, Ruf M. Local Cellular Immune Responses and Pathogenesis of Buruli Ulcer Lesions in the Experimental Mycobacterium Ulcerans Pig Infection Model. PLoS Negl Trop Dis. 2016;10:e0004678 pubmed publisher

Bachstetter A, Zhou Z, Rowe R, Xing B, Goulding D, Conley A, et al. MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses. PLoS ONE. 2016;11:e0149451 pubmed publisher

Marques A, Gabriel T, Aten J, van Roomen C, Ottenhoff R, Claessen N, et al. Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease. PLoS ONE. 2016;11:e0147208 pubmed publisher

Rajagopal R, Bligard G, Zhang S, Yin L, LUKASIEWICZ P, Semenkovich C. Functional Deficits Precede Structural Lesions in Mice With High-Fat Diet-Induced Diabetic Retinopathy. Diabetes. 2016;65:1072-84 pubmed publisher

Liu A, Hurry M, Ng O, DeFelice J, Lai H, Pearce R, et al. Bringing CLARITY to the human brain: visualization of Lewy pathology in three dimensions. Neuropathol Appl Neurobiol. 2016;42:573-87 pubmed publisher

Pelluru D, Konadhode R, Bhat N, Shiromani P. Optogenetic stimulation of astrocytes in the posterior hypothalamus increases sleep at night in C57BL/6J mice. Eur J Neurosci. 2016;43:1298-306 pubmed publisher

Brøchner C, Møllgård K. SSEA-4 and YKL-40 positive progenitor subtypes in the subventricular zone of developing human neocortex. Glia. 2016;64:90-104 pubmed publisher

Bajsarowicz K, Ahn M, Ackerman L, Dearmond B, Carlson G, Dearmond S. A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases. J Neuropathol Exp Neurol. 2012;71:449-66 pubmed publisher

Bachstetter A, Jernberg J, Schlunk A, Vila J, Hudson C, Cole M, et al. Spirulina promotes stem cell genesis and protects against LPS induced declines in neural stem cell proliferation. PLoS ONE. 2010;5:e10496 pubmed publisher