product summary
company name :
Ventana
product type :
antibody
product name :
PD-L1
catalog :
740-4859
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
SP142
reactivity :
human
application :
immunohistochemistry - paraffin section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 1
Vranic S, Ghosh N, Kimbrough J, Bilalovic N, Bender R, Arguello D, et al. PD-L1 Status in Refractory Lymphomas. PLoS ONE. 2016;11:e0166266 pubmed publisher
Morsch R, Rose M, Maurer A, Cassataro M, Braunschweig T, Knüchel R, et al. Therapeutic implications of PD-L1 expression in bladder cancer with squamous differentiation. BMC Cancer. 2020;20:230 pubmed publisher
Li C, Karantza V, Aktan G, Lala M. Current treatment landscape for patients with locally recurrent inoperable or metastatic triple-negative breast cancer: a systematic literature review. Breast Cancer Res. 2019;21:143 pubmed publisher
Cao Y, Chan K, Xiao G, Chen Y, Qiu X, Hao H, et al. Expression and clinical significance of PD-L1 and BRAF expression in nasopharyngeal carcinoma. BMC Cancer. 2019;19:1022 pubmed publisher
Arimura K, Sekine Y, Hiroshima K, Shimizu S, Shibata N, Kondo M, et al. PD-L1, FGFR1, PIK3CA, PTEN, and p16 expression in pulmonary emphysema and chronic obstructive pulmonary disease with resected lung squamous cell carcinoma. BMC Pulm Med. 2019;19:169 pubmed publisher
Rimm D, Han G, Taube J, Yi E, Bridge J, Flieder D, et al. Reanalysis of the NCCN PD-L1 companion diagnostic assay study for lung cancer in the context of PD-L1 expression findings in triple-negative breast cancer. Breast Cancer Res. 2019;21:72 pubmed publisher
Qiu L, Zheng H, Zhao X. The prognostic and clinicopathological significance of PD-L1 expression in patients with diffuse large B-cell lymphoma: a meta-analysis. BMC Cancer. 2019;19:273 pubmed publisher
Van Berckelaer C, Rypens C, van Dam P, Pouillon L, Parizel M, Schats K, et al. Infiltrating stromal immune cells in inflammatory breast cancer are associated with an improved outcome and increased PD-L1 expression. Breast Cancer Res. 2019;21:28 pubmed publisher
Ma J, Li J, Qian M, Han W, Tian M, Li Z, et al. PD-L1 expression and the prognostic significance in gastric cancer: a retrospective comparison of three PD-L1 antibody clones (SP142, 28-8 and E1L3N). Diagn Pathol. 2018;13:91 pubmed publisher
. 33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018) : Washington, D.C., USA. 7-11 November 2018. J Immunother Cancer. 2018;6:114 pubmed publisher
Ward F, Dahal L, Abu Eid R. On the Road to Immunotherapy-Prospects for Treating Head and Neck Cancers With Checkpoint Inhibitor Antibodies. Front Immunol. 2018;9:2182 pubmed publisher
Fumet J, Richard C, Ledys F, Klopfenstein Q, Joubert P, Routy B, et al. Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy. Br J Cancer. 2018;119:950-960 pubmed publisher
Kowanetz M, Zou W, Gettinger S, Koeppen H, Kockx M, Schmid P, et al. Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1). Proc Natl Acad Sci U S A. 2018;115:E10119-E10126 pubmed publisher
Shen X, Zhao B. Efficacy of PD-1 or PD-L1 inhibitors and PD-L1 expression status in cancer: meta-analysis. BMJ. 2018;362:k3529 pubmed publisher
Scorer P, Scott M, Lawson N, Ratcliffe M, Barker C, Rebelatto M, et al. Consistency of tumor and immune cell programmed cell death ligand-1 expression within and between tumor blocks using the VENTANA SP263 assay. Diagn Pathol. 2018;13:47 pubmed publisher
Chen Y, Zhang Y, Chai X, Gao J, Chen G, Zhang W, et al. Correlation between the Expression of PD-L1 and Clinicopathological Features in Patients with Thymic Epithelial Tumors. Biomed Res Int. 2018;2018:5830547 pubmed publisher
Wein L, Luen S, Savas P, Salgado R, Loi S. Checkpoint blockade in the treatment of breast cancer: current status and future directions. Br J Cancer. 2018;119:4-11 pubmed publisher
Cerbelli B, Pernazza A, Botticelli A, Fortunato L, Monti M, Sciattella P, et al. PD-L1 Expression in TNBC: A Predictive Biomarker of Response to Neoadjuvant Chemotherapy?. Biomed Res Int. 2017;2017:1750925 pubmed publisher
McGranahan N, Rosenthal R, Hiley C, Rowan A, Watkins T, Wilson G, et al. Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution. Cell. 2017;171:1259-1271.e11 pubmed publisher
Seo A, Kang B, Kwon O, Park K, Lee S, Chung H, et al. Intratumoural PD-L1 expression is associated with worse survival of patients with Epstein-Barr virus-associated gastric cancer. Br J Cancer. 2017;117:1753-1760 pubmed publisher
Alvi M, Loughrey M, Dunne P, McQuaid S, Turkington R, Fuchs M, et al. Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies. Br J Cancer. 2017;117:203-209 pubmed publisher
Joneja U, Vranic S, Swensen J, Feldman R, Chen W, Kimbrough J, et al. Comprehensive profiling of metaplastic breast carcinomas reveals frequent overexpression of programmed death-ligand 1. J Clin Pathol. 2017;70:255-259 pubmed publisher
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