product summary
company name :
Vector Laboratories
product type :
antibody
product name :
p53 Protein (CM5)
catalog :
VP-P956
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 2h
Bellelli R, Borel V, Logan C, Svendsen J, Cox D, Nye E, et al. Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis. Mol Cell. 2018;70:707-721.e7 pubmed publisher
  • immunohistochemistry; human; 1:2500; loading ...; fig 4e
Parrales A, Ranjan A, Iyer S, Padhye S, Weir S, Roy A, et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016;18:1233-1243 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 1d
  • flow cytometry; mouse; 1:50; loading ...; fig 1e
Yoshida Y, Shimizu I, Katsuumi G, Jiao S, Suda M, Hayashi Y, et al. p53-Induced inflammation exacerbates cardiac dysfunction during pressure overload. J Mol Cell Cardiol. 2015;85:183-98 pubmed publisher
  • western blot; human
Yang Z, Broz D, Noderer W, Ferreira J, Overton K, Spencer S, et al. p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress. Cell Death Differ. 2015;22:560-73 pubmed publisher
Fernández Antorán D, Piedrafita G, Murai K, Ong S, Herms A, Frezza C, et al. Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation. Cell Stem Cell. 2019;25:329-341.e6 pubmed publisher
Murai K, Skrupskelyte G, Piedrafita G, Hall M, Kostiou V, Ong S, et al. Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations. Cell Stem Cell. 2018;23:687-699.e8 pubmed publisher
Turrell F, Kerr E, Gao M, Thorpe H, Doherty G, Cridge J, et al. Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity. Genes Dev. 2017;31:1339-1353 pubmed publisher
Faller W, Jackson T, Knight J, Ridgway R, Jamieson T, Karim S, et al. mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature. 2015;517:497-500 pubmed publisher
Katyal S, Lee Y, Nitiss K, Downing S, Li Y, Shimada M, et al. Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes. Nat Neurosci. 2014;17:813-21 pubmed publisher
Muller P, Trinidad A, Timpson P, Morton J, Zanivan S, van den Berghe P, et al. Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion. Oncogene. 2013;32:1252-65 pubmed publisher
Shohat M, Ben Meir D, Lavi S. Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells. PLoS ONE. 2012;7:e32438 pubmed publisher
Ahmad I, Patel R, Liu Y, Singh L, Taketo M, Wu X, et al. Ras mutation cooperates with ?-catenin activation to drive bladder tumourigenesis. Cell Death Dis. 2011;2:e124 pubmed publisher
company information
Vector Laboratories
30 Ingold Road Burlingame, CA 94010
vector@vectorlabs.com
http://www.vectorlabs.com
headquarters: United States
Manufacturer and retailer of protein and nucleic acid labeling and detection reagents for over 35 years.