Yersinia pestis | US Biological Y2052-05 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Yersinia pestis

catalog :

Y2052-05

quantity :

500 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1.F.1

product information

Catalog Number :

Y2052-05

Product wo Prefix :

Yersinia pestis

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

500 ug

Clone # USB :

1.F.1

Isotype :

IgG1

Desc1 :

Y. pestis has a number of virulence factors that enable it to survive in humans by facilitating use of host nutrients, causing damage to host cells, and subverting phagocytosis and other host defense mechanisms. Capsular F1 antigen is a main immunochemical component of Y. pestis surface. Its synthesis is determined by pFra plasmid and induced at 370C. F1 is aggregated on the outer membrane of the Y. pestis microbe as an olygomeric protein, forming a granular layer and gradually diffusing into the environment. Capsular polymer consists of multiple similar hydrophobic protein subunits, aggregating at physiological conditions. F1 subunit of the antigen is originally synthesized from 170 amino acids and has a molecular mass 17.6Kd, then, after the elimination of the signal peptide during the secretion onto the surface, a protein with molecular mass 15.6Kd and isoelectric point 4.1 is formed. Applications: Suitable for use in Immunohistochemistry and ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen :

Purified F1 antigen of Y. pestis vaccine strain EB.

Specificity :

Recognizes capsule bearing strains of Y. pestis.

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

Concentration :

~1mg/ml

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 1.F.1 Host: mouse Concentration: ~1mg/ml Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. Purity: Purified by Protein G affinity chromatography. Immunogen: Purified F1 antigen of Y. pestis vaccine strain EB. Specificity: Recognizes capsule bearing strains of Y. pestis. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC

Storage Temperature :

-20°C