Wnt5a (Wingless-type MMTV (Mouse Mammary Tumor Virus) Integration Site Family Member)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Wnt5a (Wingless-type MMTV (Mouse Mammary Tumor Virus) Integration Site Family Member)

catalog :

W3028

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

W3028

Product wo Prefix :

Wnt5a (Wingless-type MMTV (Mouse Mammary Tumor Virus) Integration Site Family Member)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ul

Isotype :

IgG

Desc1 :

The Wnt family are a family of secreted glycoproteins that play important roles in animal development (1). There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins (2). Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways (3). The canonical Wnt/b-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family (4). Aberrant activation of Wnt signaling pathways is involved in several types of cancers (5). Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to residues surrounding Leu270 of human Wnt5a (KLH). Species sequence homology: human 100%.

Specificity :

Recognizes transfected Wnt5a protein in L cells at 45kD. Species crossreactivity: mouse.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.

Concentration :

Not determined

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: Not determined Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: Synthetic peptide corresponding to residues surrounding Leu270 of human Wnt5a (KLH). Species sequence homology: human 100%. Specificity: Recognizes transfected Wnt5a protein in L cells at 45kD. Species crossreactivity: mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Cadigan, K.M. and Nusse, R. (1997) Genes Dev. 11,3286–3305. 2. Moon, R.T. et al. (1997) Trends Genet. 13, 157–162. 3. Kohn, A.D. and Moon, R.T. (2004) Cell Calcium 38,439–446. 4. Logan, C.Y. and Nusse, R. (2004) Annu. Rev. Cell Dev.Biol. 20, 781–810. 5. Giles, R.H. et al. (2003) Biochim. Biophys. Acta. 1653,1–24.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/13/W3028_1.jpg