VDAC2 (Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, Outer Mitochondrial Membrane Protein Porin 2) | US Biological V2121-21F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

VDAC2 (Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, Outer Mitochondrial Membrane Protein Porin 2)

catalog :

V2121-21F

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

V2121-21F

Product wo Prefix :

VDAC2 (Voltage-dependent Anion-selective Channel Protein 2, VDAC-2, hVDAC2, Outer Mitochondrial Membrane Protein Porin 2)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Voltage-dependent anion channels (VDAC) are small pore-forming membrane proteins that regulate metabolite exchange across the mitochondrial outer membrane. Apart from metabolite transfer, VDAC role has also been suggested during apoptosis. VDAC2 is one of the isoforms of VDAC. It interacts with BAK and functions as a specific inhibitor of BAK-dependent mitochondrial apoptosis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 0.3-1ug/ml, observed in human brain and testis lysates on ~30kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Ca Hu Mo Po Rt

Immunogen :

Synthetic peptide corresponding to C-GHKVGLALELEA, from human VDAC2, at C-terminal (NP_003366.2).

Specificity :

Recognizes human VDCA2. Species sequence homology: Bovine, canine, mouse, porcine and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-GHKVGLALELEA, from human VDAC2, at C-terminal (NP_003366.2). Specificity: Recognizes human VDCA2. Species sequence homology: Bovine, canine, mouse, porcine and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Sarioglu H, Brandner S, Haberger M, Jacobsen C, Lichtmannegger J, Wormke M, Andrae U. Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced proteome changes in 5L rat hepatoma cells reveals novel targets of dioxin action including the mitochondrial apoptosis regulator VDAC2. Mol Cell Proteomics. 2008 Feb;7(2):394-410.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/20/V2121-21F_1.jpg