Vascular Endothelial Growth Factor Receptor 3 (VEGF3, Flt4) | US Biological V2110-20J product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Vascular Endothelial Growth Factor Receptor 3 (VEGF3, Flt4)

catalog :

V2110-20J

quantity :

100 ul

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

C28G5

The same clone is also sold as:

Cell Signaling Technology: 2638

reactivity :

human

product information

Catalog Number :

V2110-20J

Product wo Prefix :

Vascular Endothelial Growth Factor Receptor 3 (VEGF3, Flt4)

Host :

rabbit

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

C28G5

Isotype :

IgG

Desc1 :

Vascular endothelial growth factor receptor 3 (VEGFR3) is a 195kD membrane receptor tyrosine kinase. VEGF receptors are characterized by the presence of seven extracellular immunoglobulin (Ig)-like domains followed by a membrane-spanning domain and a conserved intracellular tyrosine kinase domain (1). VEGF Receptor 3 expression is largely restricted to adult lymphatic endothelium and is thought to control lymphangiogenesis (1,2). Binding of VEGF-C/VEGF-D to VEGFR3 results in transphosphorylation of tyrosine residues in its intracellular domain, recruitment of signaling molecules and activation of ERK1/2 and Akt signaling cascades (1,3). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, incubate membrane with diluted antibody in TBS, 5% BSA, 0.1% Tween-20 at 4°C with gentle shaking, overnight. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to residues surrounding Gly990 of human VEGF Receptor 3.

Specificity :

Recognizes transfected levels of human VEGFR3. Does not cross-react with other family members.

Purity :

Purified

Form :

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG Clone No: C28G5 Host: rabbit Source: human Concentration: Not determined Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol. Purity: Purified Immunogen: Synthetic peptide corresponding to residues surrounding Gly990 of human VEGF Receptor 3. Specificity: Recognizes transfected levels of human VEGFR3. Does not cross-react with other family members. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Reference :

(1) Robinson, C.J. and Stringer, S.E. (2001) J. Cell Sci.114, 853–865. (2) Valtola, R. et al. (1999) Am. J. Pathol. 154, 1381–1390. (3) Saharinen, P. and Petrova, T.V. (2004) Ann. N.Y. Acad. Sci. 1014, 76–87.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/39/V2110-20J_1.jpg