Vancomycin | US Biological V2050-02 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Vancomycin

catalog :

V2050-02

quantity :

500 ul

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

product information

Catalog Number :

V2050-02

Product wo Prefix :

Vancomycin

Host :

sheep

Product Type :

Pab

Category :

Antibodies

Size1 :

500 ul

Isotype :

IgG

Desc1 :

Vancomycin is an aminoglycoside antibiotic, used in the treatment of infections caused by Gram-positive bacteria. vancomycin is not active against Gram-negative bacteria (except some non-gonococcal species of Neisseria). The main target of this antibiotic is the D-alanyl-D-alanine terminal dipeptide of peptidoglycan precursors, used by bacteria for constructing their cell walls. This prevents the reaction used to link peptidoglycan precursors together from taking place. Vancomycin binds with the substrate, not the enzyme, in contrast to the way penicillin inhibits peptidoglycan synthesis. The large hydrophilic molecule is able to form hydrogen bond interactions with the terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Under normal circumstances, this is a five-point interaction. This binding of vancomycin to the D-Ala-D-Ala prevents cell wall synthesis in two ways. It prevents the synthesis of the long polymers of N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) that form the backbone strands of the bacterial cell wall, and it prevents the backbone polymers that do manage to form from cross-linking with each other. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen :

Vancomycin conjugated to KLH.

Specificity :

Recognizes Vancomycin.

Purity :

Serum

Form :

Supplied as a liquid, 0.09% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Pab Isotype: IgG Host: sheep Concentration: Not determined Form: Supplied as a liquid, 0.09% sodium azide. Purity: Serum Immunogen: Vancomycin conjugated to KLH. Specificity: Recognizes Vancomycin. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C