uPAR (Urokinase Plasminogen Activator Surface Receptor, U-PAR, Monocyte Activation Antigen Mo3, CD87, PLAUR, MO3) | US Biological U2610-04K product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

uPAR (Urokinase Plasminogen Activator Surface Receptor, U-PAR, Monocyte Activation Antigen Mo3, CD87, PLAUR, MO3)

catalog :

U2610-04K

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

U2610-04K

Product wo Prefix :

uPAR (Urokinase Plasminogen Activator Surface Receptor, U-PAR, Monocyte Activation Antigen Mo3, CD87, PLAUR, MO3)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

uPAR (Urokinase plasminogen activator receptor) is a 55kD glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum b-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis. Applications: Suitable for use in Neutralizaztion, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Neutralization: 2-4ug/ml Western Blot: 0.5-2ug/ml Immunoprecipitation: 5-10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to human uPAR expressed in E. coli.

Specificity :

Recognizes human uPAR at ~55kD

Purity :

Purified by affinity chromatography.

Form :

Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol. Purity: Purified by affinity chromatography. Immunogen: Recombinant protein corresponding to human uPAR expressed in E. coli. Specificity: Recognizes human uPAR at ~55kD Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

IP N WB

Storage Temperature :

-20°C