TNFSF14 (Tumor Necrosis Factor Ligand Superfamily Member 14, Herpes Virus Entry Mediator Ligand, HVEM-L, Herpes virus Entry Mediator Ligand, CD258, HVEML, LIGHT, UNQ391/PRO726) | US Biological T9162-79H product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TNFSF14 (Tumor Necrosis Factor Ligand Superfamily Member 14, Herpes Virus Entry Mediator Ligand, HVEM-L, Herpes virus Entry Mediator Ligand, CD258, HVEML, LIGHT, UNQ391/PRO726)

catalog :

T9162-79H

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

T9162-79H

Product wo Prefix :

TNFSF14 (Tumor Necrosis Factor Ligand Superfamily Member 14, Herpes Virus Entry Mediator Ligand, HVEM-L, Herpes virus Entry Mediator Ligand, CD258, HVEML, LIGHT, UNQ391/PRO726)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a Herpes virus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by Herpes virus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 1-3ug/ml, observed in human brain (cerebellum and frontal cortex) lysates on ~22kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to C-HEVNPAAHLTGANS, from human TNFSF14, at the internal region of the protein (NP_003798.2, NP_742011.1).

Specificity :

Recognizes human TNFSF14.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-HEVNPAAHLTGANS, from human TNFSF14, at the internal region of the protein (NP_003798.2, NP_742011.1). Specificity: Recognizes human TNFSF14. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Cohavy O, Zhou J, Ware CF, Targan SR LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling J. Immunol. 2005 Jan 174(2):646-53.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/20/T9162-79H_1.jpg