TROP2 (TROP-2, Tumor-associated Calcium Signal Transducer 2, Pancreatic Carcinoma Marker Protein GA733-1, Cell Surface Glycoprotein Trop-2, Membrane Component Chromosome 1 Surface Marker 1, M1S1, GA733-1, TACSTD2) | US Biological T8663-95H product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TROP2 (TROP-2, Tumor-associated Calcium Signal Transducer 2, Pancreatic Carcinoma Marker Protein GA733-1, Cell Surface Glycoprotein Trop-2, Membrane Component Chromosome 1 Surface Marker 1, M1S1, GA733-1, TACSTD2)

catalog :

T8663-95H

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

product information

Catalog Number :

T8663-95H

Product wo Prefix :

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:4000 Western Blot: 0.2-0.5ug/ml, observed in human prostate lysates on ~37kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Ca Hu Mo Po Rt

Immunogen :

Synthetic peptide corresponding to C-HYEQPTIQIELRQN, from human TROP2, at the internal region of the protein (NP_002344.2).

Specificity :

Recognizes human TROP2. Species sequence homology: Bovine, canine, mouse, porcine and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-HYEQPTIQIELRQN, from human TROP2, at the internal region of the protein (NP_002344.2). Specificity: Recognizes human TROP2. Species sequence homology: Bovine, canine, mouse, porcine and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Shimada A, Kano J, Ishiyama T, Okubo C, Iijima T, Morishita Y, Minami Y, Inadome Y, Shu Y, Sugita S, Takeuchi T, Noguchi M. Establishment of an immortalized cell line from a precancerous lesion of lung adenocarcinoma, and genes highly expressed in the early stages of lung adenocarcinoma development. Cancer Sci. 2005 Oct;96(10):668-75.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/20/T8663-95H_1.jpg