Transforming Growth Factor beta Receptor III (TGF beta Receptor III, TGF beta RIII, TGFR-3, Betaglycan) | US Biological T8250-50E product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Transforming Growth Factor beta Receptor III (TGF beta Receptor III, TGF beta RIII, TGFR-3, Betaglycan)

catalog :

T8250-50E

quantity :

250 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

T8250-50E

Product wo Prefix :

Transforming Growth Factor beta Receptor III (TGF beta Receptor III, TGF beta RIII, TGFR-3, Betaglycan)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

250 ug

Isotype :

IgG

Desc1 :

Transforming Growth Factor beta Receptor III is a transmembrane proteoglycan that binds TGF- beta with high affinity. Transforming Growth Factor beta Receptor III lacks a cytoplasmic signaling domain and functions as an accessory receptor that enhances efficient TGF-beta2 binding and signaling. A soluble form of the receptor can be released by proteolytic cleavage of the membrane-bound form. Applications Suitable for use in Western Blot, Flow Cytometry and Direct ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 0.1ug/ml using recombinant human Transforming Growth Factor beta Receptor III Flow Cytometry: 25ug/10e6 cells using PC-3 human prostate cancer cell line Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to Gly21-Asp781 from human Transforming Growth Factor beta Receptor III, expressed in NS0 cells.

Specificity :

Recognizes human Transforming Growth Factor beta Receptor III. In direct ELISAs, ~25% cross-reactivity with recombinant mouse TGF-beta RIII is observed, and <1% cross-reactivity with recombinant human TGF-beta Receptor I, recombinant human TGF-beta Receptor II, recombinant human TGF-beta Receptor IIB, and recombinant mouse TGF-beta Receptor I is observed.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 1.25ml sterile PBS.

Concentration :

~0.2mg/ml (after reconstitution)

Desc2 :

Product Type: Pab Isotype: IgG Host: goat Source: human Concentration: ~0.2mg/ml (after reconstitution) Form: Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 1.25ml sterile PBS. Purity: Purified by immunoaffinity chromatography. Immunogen: Recombinant protein corresponding to Gly21-Asp781 from human Transforming Growth Factor beta Receptor III, expressed in NS0 cells. Specificity: Recognizes human Transforming Growth Factor beta Receptor III. In direct ELISAs, ~25% cross-reactivity with recombinant mouse TGF-beta RIII is observed, and <1% cross-reactivity with recombinant human TGF-beta Receptor I, recombinant human TGF-beta Receptor II, recombinant human TGF-beta Receptor IIB, and recombinant mouse TGF-beta Receptor I is observed. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC WB

Storage Temperature :

-20°C

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/44/T8250-50E_1.jpg