TIPRL (TIP41-like Protein, Putative MAPK-activating Protein PM10, Type 2A-interacting Protein, TIP) | US Biological T5499-88C product information

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product summary

company name :

US Biological

product type :

antibody

product name :

TIPRL (TIP41-like Protein, Putative MAPK-activating Protein PM10, Type 2A-interacting Protein, TIP)

catalog :

T5499-88C

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

product information

Catalog Number :

T5499-88C

Product wo Prefix :

TIPRL (TIP41-like Protein, Putative MAPK-activating Protein PM10, Type 2A-interacting Protein, TIP)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 1-3ug/ml, lysates of cell line K562 observed on ~30kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Ca Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to C-RIDPNPADSQKSTQ, from human TIPRL, at C-terminal (NP_690866.1).

Specificity :

Recognizes human TIPRL. Species sequence homology: Bovine, canine, mouse and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-RIDPNPADSQKSTQ, from human TIPRL, at C-terminal (NP_690866.1). Specificity: Recognizes human TIPRL. Species sequence homology: Bovine, canine, mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Ehret GB, O'Connor AA, Weder A, Cooper RS, Chakravarti A, Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. Eur J Hum Genet. 2009 Dec;17(12):1650-7.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/22/T5499-88C_1.jpg