Tau 13 (Microtubule-associated Protein tau, Neurofibrillary Tangle Protein, Paired Helical Filament-tau, PHF-tau, MAPTL, MTBT1, TAU, MAPT) | US Biological T1030-10G product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Tau 13 (Microtubule-associated Protein tau, Neurofibrillary Tangle Protein, Paired Helical Filament-tau, PHF-tau, MAPTL, MTBT1, TAU, MAPT)

catalog :

T1030-10G

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13A272

reactivity :

human

product information

Catalog Number :

T1030-10G

Product wo Prefix :

Tau 13 (Microtubule-associated Protein tau, Neurofibrillary Tangle Protein, Paired Helical Filament-tau, PHF-tau, MAPTL, MTBT1, TAU, MAPT)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13A272

Isotype :

IgG1

Desc1 :

Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheimer's disease. Hyperphosphorylation of Tau is thought to be the critical event leading to the assembly of PHF. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK3. This presents the possibility that miscues in GSK3 signaling contribute to the onset of Alzheimer's disease. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunoprecipitation: 1:500 Immunohistochemistry: 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to the longest isoform of human Tau at N-terminus.

Specificity :

Recognizes human Tau-13 at ~45-60kD.

Purity :

Ascites

Form :

Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13A272 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol. Purity: Ascites Immunogen: Synthetic peptide corresponding to the longest isoform of human Tau at N-terminus. Specificity: Recognizes human Tau-13 at ~45-60kD. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

IHC IP WB

Storage Temperature :

-20°C