Syndecan 2 | US Biological S9111-40B1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Syndecan 2

catalog :

S9111-40B1

quantity :

100 ug

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

7H78

reactivity :

human

product information

Catalog Number :

S9111-40B1

Product wo Prefix :

Syndecan 2

Host :

rat

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ug

Clone # USB :

7H78

Isotype :

IgG2a

Desc1 :

Syndecans are cell surface heparan sulfate proteoglycans that act as co-receptors for growth factor binding, cell-matrix interactions, and cell-cell interactions to regulate cell adhesion, proliferation, and differentiation. Syndecan-2 interacts with matrix proteins such as laminin and fibronectin, and its cytoplasmic V region controls matrix assembly at the cell surface. Syndecan-2 is essential for angiogenic sprouting during embryogenesis and controls the growth of normal human osteoblastic cells. Syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. Applications: Suitable for use in Direct ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 8-25ug/ml Detects Syndecan-2 in paraffin-embedded normal human skin tissue sections. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to Glu19-Gly144 of human Syndecan-2 expressed in NS0 cells.

Specificity :

Recognizes human Syndecan-2. In direct ELISAs, does not crossreact with recombinant mouse Syndecan-1, recombinant human Syndecan-3 or recombinant human Syndecan-4.

Purity :

Purified by Protein G affinity chromatography from hybridoma culture supernatant.

Form :

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.

Concentration :

~0.5mg/ml (after reconstitution)

Desc2 :

Product Type: Mab Isotype: IgG2a Clone No: 7H78 Host: rat Source: human Concentration: ~0.5mg/ml (after reconstitution) Form: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS. Purity: Purified by Protein G affinity chromatography from hybridoma culture supernatant. Immunogen: Recombinant protein corresponding to Glu19-Gly144 of human Syndecan-2 expressed in NS0 cells. Specificity: Recognizes human Syndecan-2. In direct ELISAs, does not crossreact with recombinant mouse Syndecan-1, recombinant human Syndecan-3 or recombinant human Syndecan-4. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC

Storage Temperature :

-20°C