Syk | US Biological S9100-01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Syk

catalog :

S9100-01

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

S9100-01

Product wo Prefix :

Syk

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ul

Isotype :

IgG

Desc1 :

Syk is one of the well known protein tyrosine kinases. It is widely expressed and plays an important role in intracellular signal transduction in hematopoietic cells (1-3). Syk has been shown to interact with immunoreceptor tyrosine-based activation motifs (ITAMs) located in the cytoplasmic domains of immune receptors (4). It couples the activated immunoreceptors to downstream signaling events that mediate diverse cellular responses including proliferation, differentiation and phagocytosis (4). There is also evidence of a role for Syk in non-immune cells. Syk may be a potential tumor suppressor in human breast carcinomas (5). Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Hu Mo

Immunogen :

Synthetic peptide corresponding to the C-terminal sequence of human Syk (KLH).

Specificity :

Detects endogenous levels of total human Syk at 72kD. Detects both phosphorylated and nonphosphorylated forms of Syk. Does not crossreact with other members of the Syk/Zap-70 tyrosine kinase family. Species Crossreactivity: mouse.

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added.

Concentration :

Not determined

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: Not determined Form: Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added. Purity: Purified by Protein A affinity chromatography. Immunogen: Synthetic peptide corresponding to the C-terminal sequence of human Syk (KLH). Specificity: Detects endogenous levels of total human Syk at 72kD. Detects both phosphorylated and nonphosphorylated forms of Syk. Does not crossreact with other members of the Syk/Zap-70 tyrosine kinase family. Species Crossreactivity: mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Cheng, A.M., Chan, A.C., Curr. Opin. Immunol. 9: 528-533 (1997). 2. Kurosaki, T., Curr. Opin. Immunol. 9: 309-318 (1997). 3. Chu, D.H., et al., Immunol. Rev. 85: 1175-1180 (1998). 4. Turner, M., et al., Immunol. Today 21: 148-154 (2000). 5. Coopman, P.J.P., et al., Nature 406: 742-747 (2000).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/24/S9100-01_1.jpg