SFRP4 (Secreted Frizzled-related Protein 4, sFRP-4, Frizzled Protein, Human Endometrium, FrpHE) | US Biological S1012-89C product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

SFRP4 (Secreted Frizzled-related Protein 4, sFRP-4, Frizzled Protein, Human Endometrium, FrpHE)

catalog :

S1012-89C

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

product information

Catalog Number :

S1012-89C

Product wo Prefix :

SFRP4 (Secreted Frizzled-related Protein 4, sFRP-4, Frizzled Protein, Human Endometrium, FrpHE)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. Applications: Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: ELISA (Peptide): 1:32,000 Western Blot: 1-3ug/ml detects a band at ~40kD in human uterus lysates Immunohistochemistry (Paraffin): 2-4ug/ml using paraffin embedded human uterus shows grandular staining in the apical cytoplasm of the endometrial gland Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to aa TNSSCQCPHILPHQD, from an internal region of human SFRP4 (NP_003005.2). Species sequence homology: bovine, mouse, porcine and rat.

Specificity :

Recognizes human SFRP4.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to aa TNSSCQCPHILPHQD, from an internal region of human SFRP4 (NP_003005.2). Species sequence homology: bovine, mouse, porcine and rat. Specificity: Recognizes human SFRP4. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, Meissner A, Jaenisch R. Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes Dev. 2007 Dec 1;21(23):3110-22.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/42/S1012-89C_1.jpg