SEMA3E (Semaphorin-3E, KIAA0331, SEMAH) | US Biological S0668-50L product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

SEMA3E (Semaphorin-3E, KIAA0331, SEMAH)

catalog :

S0668-50L

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

product information

Catalog Number :

S0668-50L

Product wo Prefix :

SEMA3E (Semaphorin-3E, KIAA0331, SEMAH)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Immunohistochemistry (Paraffin): 4-6ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Ca Hu Mo Po Rt

Immunogen :

Synthetic peptide corresponding to C-NGGRYGTTKDYPDD, from human SEMA3E, at the internal region of the protein (NP_036563.1, NP_001171600.1).

Specificity :

Recognizes human SEMA3E. Species sequence homology: Canine, mouse, porcine and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-NGGRYGTTKDYPDD, from human SEMA3E, at the internal region of the protein (NP_036563.1, NP_001171600.1). Specificity: Recognizes human SEMA3E. Species sequence homology: Canine, mouse, porcine and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC

Storage Temperature :

-20°C

Reference :

1. Gu C, Yoshida Y, Livet J, Reimert DV, Mann F, Merte J, Henderson CE, Jessell TM, Kolodkin AL, Ginty DD. Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science. 2005 Jan 14;307(5707):265-8. Epub 2004 Nov 18.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/46/S0668-50L_1.jpg