RRAGC (Ras-related GTP Binding C, AU041672, GTPase-interacting Protein 2, GTR2, Rag C Protein, RAGC, TIB929, YGR163W) | US Biological R9044-01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

RRAGC (Ras-related GTP Binding C, AU041672, GTPase-interacting Protein 2, GTR2, Rag C Protein, RAGC, TIB929, YGR163W)

catalog :

R9044-01

quantity :

100 ul

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

10g90(D8H5)

reactivity :

human

product information

Catalog Number :

R9044-01

Product wo Prefix :

RRAGC (Ras-related GTP Binding C, AU041672, GTPase-interacting Protein 2, GTR2, Rag C Protein, RAGC, TIB929, YGR163W)

Host :

rabbit

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

10g90(D8H5)

Isotype :

IgG

Desc1 :

mTORC1 kinase complex is a critical component in regulating cell growth (1,2). Its activity is modulated by energy levels, growth factors and amino acids (3,4). Recent studies found that RagA, RagB, RagC and RagD, the four related GTPases, interact with raptor in mTORC1 (1,2). These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals (1,2). Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunofluorescence. Other applications not tested. Recommended Dilution: Immunofluorescence (IF-IC): 1:100 Flow Cytometry: 1:400 Western Blot: 1:1000 Immunoprecipitation: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mk Mo Rt

Immunogen :

Synthetic peptide corresponding to residues in the N-terminus of human RagC.

Specificity :

Recognizes endogenous levels of total human RagC protein. Species crossreactivity: mouse, rat and monkey

Purity :

Purified

Form :

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG Clone No: 10g90(D8H5) Host: rabbit Source: human Concentration: Not determined. Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol. Purity: Purified Immunogen: Synthetic peptide corresponding to residues in the N-terminus of human RagC. Specificity: Recognizes endogenous levels of total human RagC protein. Species crossreactivity: mouse, rat and monkey Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FC IF IP WB

Storage Temperature :

-20°C

Reference :

1. Sancak, Y. et al. (2008) Science 320, 1496-501. 2. Kim, E. et al. (2008) Nat Cell Biol 10, 935-45. 3. Hay, N. and Sonenberg, N. (2004) Genes Dev 18, 1926-45. 4. Wullschleger, S. et al. (2006) Cell 124, 471-84.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/6/R9044-01_1.jpg