antibody

REXO1 (RNA Exonuclease 1 Homolog, Elongin-A-binding Protein 1, EloA-BP1, Transcription Elongation Factor B Polypeptide 3-binding Protein 1, ELOABP1, KIAA1138, TCEB3BP1)

R2998-04D

100 ug

polyclonal

domestic goat

nonconjugated

human, mouse, rat

REXO1 (RNA Exonuclease 1 Homolog, Elongin-A-binding Protein 1, EloA-BP1, Transcription Elongation Factor B Polypeptide 3-binding Protein 1, ELOABP1, KIAA1138, TCEB3BP1)

goat

Pab

Antibodies

100 ug

IgG

REXO1 is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221aa and its mRNA is ubiquitously expressed. It is a putative stem cell marker and is highly expressed in embryonic and adult stem cells. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Ca Hu Mo Rt

Synthetic peptide corresponding to C-KVREDAKTKR, from REXO1, at C-terminal (NP_065746.2).

Recognizes REXO1. Species sequence homology: Canine, human, mouse and rat.

Purified by immunoaffinity chromatography

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

~0.5mg/ml

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-KVREDAKTKR, from REXO1, at C-terminal (NP_065746.2). Specificity: Recognizes REXO1. Species sequence homology: Canine, human, mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E

-20°C

1. Palmqvist L, Glover CH, Hsu L, Lu M, Bossen B, Piret JM, Humphries RK, Helgason CD. Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. Stem Cells. 2005 May;23(5):663-80.