Ribosomal Protein S3 | US Biological R2031-28T product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Ribosomal Protein S3

catalog :

R2031-28T

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

R2031-28T

Product wo Prefix :

Ribosomal Protein S3

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ul

Isotype :

IgG

Desc1 :

Ribosomal protein S3 (rpS3) is a component of the 40S ribosomal subunit and is involved in translation. HSP90 interacts with both the N-terminus and C-terminus of rpS3, preventing its ubiquitination and degradation and thereby retaining the integrity of the ribosome (1). rpS3 has also been shown to function as an endonuclease during DNA damage repair (2,3). Furthermore, overexpression of rpS3 sensitizes lymphocytic cells to cytokine-induced apoptosis, indicating a third role for rpS3 during apoptosis (4). The functions of rpS3 during DNA damage repair and apoptosis have been mapped to two distinct domains (4). Applications: Suitable for use in Immunofluorescence/Immunocytochemistry and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunofluorescence/Immunocytochemistry: 1:25 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mk Mo Rt

Immunogen :

Synthetic peptide derived from the sequence of human ribosomal protein S3.

Specificity :

Recognizes endogenous levels of human total ribosomal protein S3 at 27kD. Species Crossreactivity: mouse, rat and monkey

Purity :

Purified by peptide affinity chromatography.

Form :

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.

Concentration :

Not determined

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: Not determined Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. Purity: Purified by peptide affinity chromatography. Immunogen: Synthetic peptide derived from the sequence of human ribosomal protein S3. Specificity: Recognizes endogenous levels of human total ribosomal protein S3 at 27kD. Species Crossreactivity: mouse, rat and monkey Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

IC IF WB

Storage Temperature :

-20°C

Reference :

(1) Kim, T.S. et al. (2006) Mol Biol Cell 17, 824–33. (2) Kim, J. et al. (1995) J Biol Chem 270, 13620–9. (3) Choi, S.H. et al. (2006) FEBS Lett 580, 6755–62. (4) Jang, C.Y. et al. (2004) FEBS Lett 560, 81–5.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/49/R2031-28T_1.jpg