antibody

Podocalyxin (Podocalyxin-like protein-1, PC, PCLP, PCLP1, PODXL, MGC138240, GCTM-2 Antigen Gp200)

P9104-88F

100 ug

polyclonal

domestic goat

nonconjugated

human, mouse, rat

Podocalyxin (Podocalyxin-like protein-1, PC, PCLP, PCLP1, PODXL, MGC138240, GCTM-2 Antigen Gp200)

goat

Pab

Antibodies

100 ug

IgG

Podocalyxin, also known as Podocalyxin-like protein-1 (PCLP1 or PODXL), is a type I transmembrane glycoprotein. It belongs to the CD34/Podocalyxin family of sialomucins that share structural similarity and sequence homology. Podocalyxin is a major sialoprotein in the podocytes of the kidney glomerulus and is also expressed by both endothelium and multipotent hematopoietic progenitors. It has been identified as a novel cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Western Blot: 1-3ug/ml, observed in human, mouse and rat kidney lysates on ~160kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Ca Hu Mo Rt

Synthetic peptide corresponding to C-DNLTKDDLDEEEDTH, from PODXL, at C-terminal (NP_001018121.1, NP_005388.2).

Recognizes human PODXL. Species Crossreactivity: Mouse and rat. Species sequence homology: Canine.

Purified by immunoaffinity chromatography

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

~0.5mg/ml

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-DNLTKDDLDEEEDTH, from PODXL, at C-terminal (NP_001018121.1, NP_005388.2). Specificity: Recognizes human PODXL. Species Crossreactivity: Mouse and rat. Species sequence homology: Canine. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E WB

-20°C

1. Nielsen JS, Graves ML, Chelliah S, Vogl AW, Roskelley CD, McNagny KM. The CD34-Related Molecule Podocalyxin Is a Potent Inducer of Microvillus Formation. PLoS ONE. 2007 Feb 21;2:e237.

https://usbio-images.r.worldssl.net/prodimages/33/P9104-88F_1.jpg