Alkaline Phosphatase discontinued | US Biological P4071-39 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Alkaline Phosphatase discontinued

catalog :

P4071-39

quantity :

1 ml

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

product information

Catalog Number :

P4071-39

Product wo Prefix :

Alkaline Phosphatase discontinued

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

1 ml

Isotype :

IgG

Desc1 :

Alkaline phosphatase (AP) is a ubiquitously expressed enzyme which removes phosphate groups from target molecules, including DNA, RNA and alkaloids, under alkaline conditions, and is present at higher concentrations in the placenta (placental AP), intestines (intestinal AP) and liver/bone/kidney (tissue non-specific AP). In vivo studies have identified CIAP as a potential therapeutic agent for the treatment of lipopolysaccharide (LPS)-mediated inflammation and sepsis, due to the ability of CIAP to neutralise and thereby detoxify (LPS). Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilution: ELISA: 1:1000 -1:10000 Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies I1903-30U: IgG, H&L, X-adsorbed (HRP) ShxRb Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

Intestinal Alkaline Phosphatase

Immunogen :

Highly pure calf intestinal alkaline phosphatase.

Specificity :

Recognizes calf intestinal alkaline phosphatase- (CIAP), a membrane-bound hydrolase enzyme highly expressed by intestinal mucosa. Species crossreactivity: porcine. Detects a band of ~67kD in porcine microvillar membranes.

Purity :

Purified by Immunoaffinity chromatography

Form :

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

Concentration :

~5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: bovine Concentration: ~5mg/ml Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. Purity: Purified by Immunoaffinity chromatography. Immunogen: Highly pure calf intestinal alkaline phosphatase. Specificity: Recognizes calf intestinal alkaline phosphatase- (CIAP), a membrane-bound hydrolase enzyme highly expressed by intestinal mucosa. Species crossreactivity: porcine. Detects a band of ~67kD in porcine microvillar membranes. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Braccia, A. et al. (2003) Microvillar membrane microdomains exist at physiological temperature. Role of galectin-4 as lipid raft stabilizer revealed by "superrafts". J. Biol. Chem. 278: 15679-15684. 2. Beumer, C. et al. (2003) Calf intestinal alkaline phosphatase, a novel therapeutic drug for lipopolysaccharide (LPS)-mediated diseases, attenuates LPS toxicity in mice and piglets. J. Pharmacol. Exp. Ther. 307: 737-744.