PRDX2 (Peroxiredoxin 2, Prx2, Peroxiredoxin-2, Natural Killer Cell-enhancing Factor B, NKEF-B, PRP, Thiol-specific Antioxidant Protein, TSA, Thioredoxin Peroxidase 1, Thioredoxin-dependent Peroxide Reductase 1, NKEFB, TDPX1) | US Biological P3352-12K product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PRDX2 (Peroxiredoxin 2, Prx2, Peroxiredoxin-2, Natural Killer Cell-enhancing Factor B, NKEF-B, PRP, Thiol-specific Antioxidant Protein, TSA, Thioredoxin Peroxidase 1, Thioredoxin-dependent Peroxide Reductase 1, NKEFB, TDPX1)

catalog :

P3352-12K

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13A12

reactivity :

human

product information

Catalog Number :

P3352-12K

Product wo Prefix :

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13A12

Isotype :

IgG2b,k

Desc1 :

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the aa sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30kD in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Positive Control: HeLa Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rt

Immunogen :

Recombinant corresponding to human Peroxiredoxin 2 expressed in E.coli.

Specificity :

Recognizes human Peroxiredoxin 2. Species Crossreactivity: mouse and rat.

Purity :

Ascites

Form :

Supplied as a liquid in HEPES, 0.15M sodium chloride, 0.01% BSA, 0.03% sodium azide, 50% glycerol.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG2b, k Clone No: 13A12 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid in HEPES, 0.15M sodium chloride, 0.01% BSA, 0.03% sodium azide, 50% glycerol. Purity: Ascites Immunogen: Recombinant corresponding to human Peroxiredoxin 2 expressed in E.coli. Specificity: Recognizes human Peroxiredoxin 2. Species Crossreactivity: mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Reference :

1. Wood, Z. A. et al. (2003) Trends Biochem Sci. 28(1):32-40. 2. Rhee Sue Goo, et al (2001) IUBMB life 52:35-41. 3. Min Hee Choi, et al (2005) Nature letters 435(19):347-353.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/35/P3352-12K_1.jpg