PDK1 (PDHK1, [Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 1, Mitochondrial, Pyruvate Dehydrogenase Kinase Isoform 1) | US Biological P3123-02Y product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PDK1 (PDHK1, [Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 1, Mitochondrial, Pyruvate Dehydrogenase Kinase Isoform 1)

catalog :

P3123-02Y

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

P3123-02Y

Product wo Prefix :

PDK1 (PDHK1, [Pyruvate Dehydrogenase [Lipoamide]] Kinase Isozyme 1, Mitochondrial, Pyruvate Dehydrogenase Kinase Isoform 1)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. (provided by RefSeq). Tissue specificity: Expressed predominantly in the heart. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Western Blot: 1-3ug/ml, observed in rat heart lysates on ~65-70kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Ca Hu Mo Po Rt

Immunogen :

Synthetic peptide corresponding to C-DFKDKSAEDAK, from PDK1, at the internal region of the protein (NP_002601.1).

Specificity :

Recognizes human PDK1. Species Crossreactivity: Rat. Species sequence homology: Bovine, canine, mouse and porcine.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-DFKDKSAEDAK, from PDK1, at the internal region of the protein (NP_002601.1). Specificity: Recognizes human PDK1. Species Crossreactivity: Rat. Species sequence homology: Bovine, canine, mouse and porcine. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science. 2005 Feb 18;307(5712):1098-101.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/41/P3123-02Y_1.jpg