Osteopontin (OPN, Bone Sialoprotein I, BSP-1, Secreted Phosphoprotein 1, SPP1, Early T-Lymphocyte Activation 1) | US Biological O8064-06 product information

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product summary

company name :

US Biological

product type :

antibody

product name :

Osteopontin (OPN, Bone Sialoprotein I, BSP-1, Secreted Phosphoprotein 1, SPP1, Early T-Lymphocyte Activation 1)

catalog :

O8064-06

quantity :

20 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

O8064-06

Product wo Prefix :

Osteopontin (OPN, Bone Sialoprotein I, BSP-1, Secreted Phosphoprotein 1, SPP1, Early T-Lymphocyte Activation 1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

20 ul

Isotype :

IgG

Desc1 :

Osteopontin is a single-chain polypeptide with a molecular weight of ~35kD. It is a glycoprotein first identified in osteoblasts. It is biosynthesized by a variety of tissue types including preosteoblasts, osteoblasts, osteocytes, extraosseous cells in the inner ear, brain, kidney, deciduum, placenta, odontoblasts, some bone marrow cells, hypertrophic chondrocytes, macrophages, smooth muscle, and endothelial cells. Osteopontin is overexpressed in a variety of cancers, including lung cancer, breast cancer, colorectal cancer, stomach cancer, ovarian cancer, melanoma and mesothelioma. It may contribute to kidney stone formation and both glomerulonephritis and tubulointerstitial nephritis and is also found in atheromatous plaques within arteries. Research has implicated osteopontin in excessive scar-forming and a gel has been developed to inhibit its effect. Applications: Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:1000 Immunohistochemistry (Paraffin): 1:100-1:1500 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Hu Mo

Immunogen :

Synthetic peptide corresponding to aa59-74, PSKSNESHDHMDDMDD, of mature human osteopontin (P10451).

Specificity :

Recognizes human osteopontin. Does not crossreact with human osteonectin or bone sialoprotein. Species Crossreactivity: mouse

Purity :

Serum

Form :

Supplied as a lyophilized powder. Reconstitute with 20ul sterile ddH2O.

Concentration :

Not Determined

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: Not Determined Form: Supplied as a lyophilized powder. Reconstitute with 20ul sterile ddH2O. Purity: Serum Immunogen: Synthetic peptide corresponding to aa59-74, PSKSNESHDHMDDMDD, of mature human osteopontin (P10451). Specificity: Recognizes human osteopontin. Does not crossreact with human osteonectin or bone sialoprotein. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/49/O8064-06_1.jpg