NPTXR (Neuronal Pentraxin Receptor, NPR) | US Biological N5379-08R product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NPTXR (Neuronal Pentraxin Receptor, NPR)

catalog :

N5379-08R

quantity :

100 ug

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

N5379-08R

Product wo Prefix :

NPTXR (Neuronal Pentraxin Receptor, NPR)

Host :

sheep

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

NPTXR (Neuronal Pentraxin Receptor; also NPR) is a 65kD, type II transmembrane glycoprotein that binds Neuronal Pentraxins 1 and 2. It is expressed on cerebellar Purkinje and granule cells, and hippocampal neurons of the CA1, CA3 and dentate gyrus regions. Human NPTXR is 499 amino acids (aa) in length. It contains a two aa cytoplasmic tail, a 21aa transmembrane segment, and a 476aa extracellular region with one Pentraxin domain (aa295-499). One alternate start site exists at Met12, and a 55kD soluble form (possibly beginning at Gln56) may be generated by proteolytic cleavage. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.1ug/ml Immunohistochemistry: 5-15ug/ml using immersion fixed paraffin-embedded sections of human brain (hippocampus) Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to Ala24-Lys499 of human NPTXR, expressed in NS0 cells. Species Sequence Homology: mouse (87%)

Specificity :

Recognizes human NPTXR. Shows <5% crossreacitvity with rhNPTX1 and rhNPTX2 in direct ELISA.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.

Concentration :

~0.2mg/ml (after reconstitution)

Desc2 :

Product Type: Pab Isotype: IgG Host: sheep Source: human Concentration: ~0.2mg/ml (after reconstitution) Form: Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 500ul sterile PBS. Purity: Purified by immunoaffinity chromatography. Immunogen: Recombinant protein corresponding to Ala24-Lys499 of human NPTXR, expressed in NS0 cells. Species Sequence Homology: mouse (87%) Specificity: Recognizes human NPTXR. Shows <5% crossreacitvity with rhNPTX1 and rhNPTX2 in direct ELISA. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C