Neutrophil Defensin 1, 3 (Defensin, alpha 1, HNP-1, HP-1, HP1, DEFA1, DEF1, DEFA2, MRS, DEFA1B/Defensin, alpha 3, HNP-3, HP-3, HP3, DEFA3, DEF3) | US Biological N5377-03P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Neutrophil Defensin 1, 3 (Defensin, alpha 1, HNP-1, HP-1, HP1, DEFA1, DEF1, DEFA2, MRS, DEFA1B/Defensin, alpha 3, HNP-3, HP-3, HP3, DEFA3, DEF3)

catalog :

N5377-03P

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

N5377-03P

Product wo Prefix :

Neutrophil Defensin 1, 3 (Defensin, alpha 1, HNP-1, HP-1, HP1, DEFA1, DEF1, DEFA2, MRS, DEFA1B/Defensin, alpha 3, HNP-3, HP-3, HP3, DEFA3, DEF3)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Defensin alpha 1, otherwise known as HNP-1, is a secreted cationic antimicrobial peptide and member of the alpha-defensin family, which plays an important role in the innate immune response against microbial infections. Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. Applications: Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:128,000 Western Blot: 1-3ug/ml ~10kDa band observed in human Spleen lysates Immunohistochemistry (Paraffin): 3-6ug/ml using human thymus. Requires HIER using sodium citrate buffer pH6.0 prior to staining. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to C-DESLAPKHPGSRKN, of human Neutrophil Defensin 1, 3 at the internal region of the protein.

Specificity :

Recognizes human Neutrophil Defensin 1, 3.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-DESLAPKHPGSRKN, of human Neutrophil Defensin 1, 3 at the internal region of the protein. Specificity: Recognizes human Neutrophil Defensin 1, 3. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Chang TL, Vargas J Jr, DelPortillo A, Klotman ME. Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity. J Clin Invest. 2005 Mar;115(3):765-73.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/16/N5377-03P_1.jpg