NMDAR2B (Glutamate [NMDA] Receptor Subunit epsilon-2, N-methyl D-aspartate Receptor Subtype 2B, NMDAR2B, NR2B, N-methyl-D-aspartate Receptor Subunit 3, NR3, hNR3, GRIN2B) | US Biological N2904-35S product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NMDAR2B (Glutamate [NMDA] Receptor Subunit epsilon-2, N-methyl D-aspartate Receptor Subtype 2B, NMDAR2B, NR2B, N-methyl-D-aspartate Receptor Subunit 3, NR3, hNR3, GRIN2B)

catalog :

N2904-35S

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

product information

Catalog Number :

N2904-35S

Product wo Prefix :

NMDAR2B (Glutamate [NMDA] Receptor Subunit epsilon-2, N-methyl D-aspartate Receptor Subtype 2B, NMDAR2B, NR2B, N-methyl-D-aspartate Receptor Subunit 3, NR3, hNR3, GRIN2B)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 2-4ug/ml, observed in rat brain lysates on ~170kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to C-KDAHEKDDFHHLS, from rat GRIN2B, at the internal region of the protein (NP_000825.1). Species sequence homology: canine, human and mouse

Specificity :

Recognizes rat GRIN2B.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: goat Source: rat Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-KDAHEKDDFHHLS, from rat GRIN2B, at the internal region of the protein (NP_000825.1). Species sequence homology: canine, human and mouse Specificity: Recognizes rat GRIN2B. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Arning L, Kraus PH, Valentin S, Saft C, Andrich J, Epplen JT. NR2A and NR2B receptor gene variations modify age at onset in Huntington disease. Neurogenetics. 2005 Feb; 6(1):25-8. Epub 2004

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/49/N2904-35S_1.jpg