This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
NMDAR1 (GRIN1, Glutamate [NMDA] Receptor Subunit zeta-1, N-methyl-D-aspartate Receptor Subunit NR1, NMD-R1)
catalog :
N2904-35F4
quantity :
100 ug
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
product information
Catalog Number :
N2904-35F4
Product wo Prefix :
NMDAR1 (GRIN1, Glutamate [NMDA] Receptor Subunit zeta-1, N-methyl-D-aspartate Receptor Subunit NR1, NMD-R1)
Host :
goat
Product Type :
Pab
Category :
Antibodies
Size1 :
100 ug
Isotype :
IgG
Desc1 :
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:1000
Western Blot: 2-4ug/ml, observed in rat brain lysates on ~110kD bands
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Rt
Immunogen :
Synthetic peptide corresponding to C-TQERVNNSNKKE, from rat GRIN1, at the internal region of the protein (NP_000823.4, NP_067544.1, NP_015566.1). Species sequence homology: Canine, human and mouse
Specificity :
Recognizes rat GRIN1.
Purity :
Purified by immunoaffinity chromatography
Form :
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Concentration :
~0.5mg/ml
Desc2 :
Product Type: Pab
Isotype: IgG
Host: goat
Source: rat
Concentration: ~0.5mg/ml
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity: Purified by immunoaffinity chromatography.
Immunogen: Synthetic peptide corresponding to C-TQERVNNSNKKE, from rat GRIN1, at the internal region of the protein (NP_000823.4, NP_067544.1, NP_015566.1). Species sequence homology: Canine, human and mouse
Specificity: Recognizes rat GRIN1.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E WB
Storage Temperature :
-20°C
Reference :
1. Rajji T, Chapman D, Eichenbaum H, Greene R. The role of CA3 hippocampal NMDA receptors in paired associate learning. J Neurosci. 2006 Jan 18; 26(3):908-15.
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/2/N2904-35F4_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
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