NIK (Mitogen-activated Protein Kinase Kinase Kinase 14, NF-kappa-beta-inducing Kinase, HsNIK, Serine/Threonine-protein Kinase NIK, MAP3K14) | US Biological N2567-01K product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NIK (Mitogen-activated Protein Kinase Kinase Kinase 14, NF-kappa-beta-inducing Kinase, HsNIK, Serine/Threonine-protein Kinase NIK, MAP3K14)

catalog :

N2567-01K

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

N2567-01K

Product wo Prefix :

NIK (Mitogen-activated Protein Kinase Kinase Kinase 14, NF-kappa-beta-inducing Kinase, HsNIK, Serine/Threonine-protein Kinase NIK, MAP3K14)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK was initially isolated from a human B cell cDNA library and contains 795aa with an apparent molecular weight of slightly more than 97kD on SDS gel. NIK is a serine/threonine kinase and its kinase activity contributes to IkB phosphorylation. The carboxyl terminal segment of NIK binds TRAF2. A mutant NIK with intact carboxyl terminus but without the two lysine residues at its catalytic domain serves as a dominant-negative inhibitor for NF-kB activation. NIK also interacts with TRAF6 and mediates IL-1-induced NF-kB activation. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Ca Hm Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to aa927 from human NIK.

Specificity :

Recognizes human NIK. Species Crossreactivity: mouse, rat, canine and hamster.

Purity :

Purified by affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol. Purity: Purified by affinity chromatography. Immunogen: Synthetic peptide corresponding to aa927 from human NIK. Specificity: Recognizes human NIK. Species Crossreactivity: mouse, rat, canine and hamster. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/1/N2567-01K_1.jpg