MOG (Myelin-oligodendrocyte Glycoprotein) | US Biological M9758-08T product information

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product summary

company name :

US Biological

product type :

antibody

product name :

MOG (Myelin-oligodendrocyte Glycoprotein)

catalog :

M9758-08T

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

M9758-08T

Product wo Prefix :

MOG (Myelin-oligodendrocyte Glycoprotein)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). MOG protein constitutes only 0.01-0.5% of the CNS myelin proteins, has mass of 27kD, and is located in the outermost layer of myelin sheath. Mouse MOG is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to mouse MOG has been observed in induced experimental autoimmune encephalomyelitis (EAE) in C57/BL6, 129/Sv, B6, and SJL mice. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 0.03-1ug/ml, observed in human brain lysates on ~26kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Hu Mo Po Rt

Immunogen :

Synthetic peptide corresponding to C-AGQFLEELRNPF, from human MOG, at C-terminal (NP_996532.2, NP_996535.2, NP_001008229.1).

Specificity :

Recognizes human MOG. Species sequence homology: Bovine, mouse, porcine and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-AGQFLEELRNPF, from human MOG, at C-terminal (NP_996532.2, NP_996535.2, NP_001008229.1). Specificity: Recognizes human MOG. Species sequence homology: Bovine, mouse, porcine and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Zai G, King N, Wigg K, Couto J, Wong GW, Honer WG, Barr CL, Kennedy JL. Genetic study of the myelin oligodendrocyte glycoprotein (MOG) gene in schizophrenia. Genes Brain Behav. 2005 Feb;4(1):2-9.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/8/M9758-08T_1.jpg