MSH2 (DNA Mismatch Repair Protein Msh2, hMSH2, MutS Protein Homolog 2) | US Biological M4692-34B product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MSH2 (DNA Mismatch Repair Protein Msh2, hMSH2, MutS Protein Homolog 2)

catalog :

M4692-34B

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

M4692-34B

Product wo Prefix :

MSH2 (DNA Mismatch Repair Protein Msh2, hMSH2, MutS Protein Homolog 2)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

DNA mismatch repair genes have been found to be associated with hereditary nonpolyposis colorectal cancer (HNPCC). Inherited mutations in the MSH2 were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability suggests that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1-4ug/ml Immunoprecipitation: 15-25ug/ml Immunohistochemistry: 15-25ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to aa1-50 from human MSH2.

Specificity :

Recognizes human MSH2. Species Crossreactivity: mouse and rat.

Purity :

Purified by affinity chromatography.

Form :

Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol.

Concentration :

~0.1mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: ~0.1mg/ml Form: Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol. Purity: Purified by affinity chromatography. Immunogen: Synthetic peptide corresponding to aa1-50 from MSH2. Specificity: Recognizes human MSH2. Species Crossreactivity: mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

IHC IP WB

Storage Temperature :

-20°C