antibody

MRP9 (Multidrug Resistance-associated Protein 9, ATP-binding Cassette Sub-family C Member 12, ABCC12)

M4688-39C

100 ug

polyclonal

domestic goat

nonconjugated

human, mouse, rat

MRP9 (Multidrug Resistance-associated Protein 9, ATP-binding Cassette Sub-family C Member 12, ABCC12)

goat

Pab

Antibodies

100 ug

IgG

Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene. This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Bo Ca Hu Mo Rt

Synthetic peptide corresponding to C-EFDKPEVLAEKPD, from ABCC12, at the internal region (near C-terminal) of the protein (NP_150229.2).

Recognizes ABCC12. Species sequence homology: Bovine, canine, human, mouse and rat.

Purified by immunoaffinity chromatography

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

~0.5mg/ml

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-EFDKPEVLAEKPD, from ABCC12, at the internal region (near C-terminal) of the protein (NP_150229.2). Specificity: Recognizes ABCC12. Species sequence homology: Bovine, canine, human, mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E

-20°C

1. Yabuuchi H, Shimizu H, Takayanagi S, Ishikawa T. Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12. Biochem Biophys Res Commun. 2001 Nov 9;288(4):933-9.