ABCC4 (Multidrug Resistance-associated Protein 4, ATP-binding Cassette Sub-family C Member 4, MRP/cMOAT-related ABC transporter, Multi-specific Organic Anion Transporter B, MOAT-B, ABCC4) | US Biological M4688-25J product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ABCC4 (Multidrug Resistance-associated Protein 4, ATP-binding Cassette Sub-family C Member 4, MRP/cMOAT-related ABC transporter, Multi-specific Organic Anion Transporter B, MOAT-B, ABCC4)

catalog :

M4688-25J

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, rat

product information

Catalog Number :

M4688-25J

Product wo Prefix :

ABCC4 (Multidrug Resistance-associated Protein 4, ATP-binding Cassette Sub-family C Member 4, MRP/cMOAT-related ABC transporter, Multi-specific Organic Anion Transporter B, MOAT-B, ABCC4)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 1-3ug/ml Immunohistochemistry (Paraffin): 2-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to CNGQPSTLTIFETAL, from ABCC4, at C-terminal (NP_005836.2).

Specificity :

Recognizes human ABCC4. Species Crossreactivity: rat. Species sequence homology: Mouse.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to CNGQPSTLTIFETAL, from ABCC4, at C-terminal (NP_005836.2). Specificity: Recognizes human ABCC4. Species Crossreactivity: rat. Species sequence homology: Mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Xu S, Weerachayaphorn J, Cai SY, Soroka CJ, Boyer JL. Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression. Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G126-35.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/7/M4688-25J_1.jpg