MAPK1 (Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK-2, MAP Kinase Isoform p42, p42-MAPK, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, ERK2, PRKM1, PRKM2) | US Biological M2351-80K1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MAPK1 (Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, ERT1, Extracellular Signal-regulated Kinase 2, ERK-2, MAP Kinase Isoform p42, p42-MAPK, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, ERK2, PRKM1, PRKM2)

catalog :

M2351-80K1

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

product information

Catalog Number :

M2351-80K1

Product wo Prefix :

URL USB :

www.usbio.net/antibodies/M2351-80K1/MAPK1-Mitogenactivated-Protein-Kinase-1-MAP-Kinase-1-MAPK-1-ERT1-Extracellular-Signalregulated-Kinase-2-ERK2-MAP-Kinase-Isoform-p42-p42MAPK-Mitogenactivated-Protein-Kinase-2-MAP-Kinase-2-MAPK-2-ERK2-PRKM1-PRKM2

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

MAPK1 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Applications:. Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution:. ELISA: 1:8000. Western Blot: 0.5-2ug/ml, observed in human cervix epitheloid carcinoma HeLa and epatoblastoma HepG2 lysates on ~38kD bands. Optimal dilutions to be determined by the researcher. Storage and Stability:. May be stored at 4 C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Ca Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to CAAGPEMVRGQVF, from human MAPK1, at the internal region of the protein (NP_002736.3, NP_620407.1).

Specificity :

Recognizes human MAPK1. Species sequence homology: Bovine, canine, mouse and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab. Host: goat. Source: human. Concentration: ~0.5mg/ml. Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to CAAGPEMVRGQVF, from human MAPK1, at the internal region of the protein (NP_002736.3, NP_620407.1). Specificity: Recognizes human MAPK1. Species sequence homology: Bovine, canine, mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20 C

Reference :

1. Lee SM, Nguyen TH, Park MH, Kim KS, Cho KJ, Moon DC, Kim HY, Yoon do Y, Hong JT. EPO receptor-mediated ERK kinase and NF-kappaB activation in erythropoietin-promoted differentiation of astrocytes. Biochem Biophys Res Commun. 2004 Aug 6;320(4):1087-95.

Picture 1 File Name :

usbio-images.r.worldssl.net/prodimages/48/M2351-80K1_1.jpg