MBL-C (Mannose-binding Lectin C, MBP-C, Collectin-1, MBP1, Mannan-binding Protein, MBL2, COLEC1) discontinued | US Biological M2250-01G product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MBL-C (Mannose-binding Lectin C, MBP-C, Collectin-1, MBP1, Mannan-binding Protein, MBL2, COLEC1) discontinued

catalog :

M2250-01G

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

M2250-01G

Product wo Prefix :

MBL-C (Mannose-binding Lectin C, MBP-C, Collectin-1, MBP1, Mannan-binding Protein, MBL2, COLEC1) discontinued

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:4000 Western Blot: 1-3ug/ml, observed in human heart and kdney lysates on ~26kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to STSHLAVCEFPI, from human MBL2, at C-terminal (NP_000233.1).

Specificity :

Recognizes human MBL2.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to STSHLAVCEFPI, from human MBL2, at C-terminal (NP_000233.1). Specificity: Recognizes human MBL2. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Saevarsdottir S, Oskarsson OO, Aspelund T, Eiriksdottir G, Vikingsdottir T, Gudnason V, Valdimarsson H. Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk. J Exp Med. 2005 Jan 3;201(1):117-25. Epub 2004 Dec 28.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/16/M2250-01G_1.jpg