MAD2L1 (Mitotic Spindle Assembly Checkpoint Protein MAD2A, HsMAD2, Mitotic Arrest Deficient 2-like Protein 1, MAD2-like Protein 1, MAD2) | US Biological M1499-15J product information

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product summary

company name :

US Biological

product type :

antibody

product name :

MAD2L1 (Mitotic Spindle Assembly Checkpoint Protein MAD2A, HsMAD2, Mitotic Arrest Deficient 2-like Protein 1, MAD2-like Protein 1, MAD2)

catalog :

M1499-15J

quantity :

100 ug

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

product information

Catalog Number :

M1499-15J

Product wo Prefix :

MAD2L1 (Mitotic Spindle Assembly Checkpoint Protein MAD2A, HsMAD2, Mitotic Arrest Deficient 2-like Protein 1, MAD2-like Protein 1, MAD2)

Host :

goat

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 2-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Bo Ca Hu Mo Po Rt

Immunogen :

Synthetic peptide corresponding to C-KVNSMVAYKIPVND, from human MAD2L1, at C-terminal (NP_002349.1).

Specificity :

Recognizes human MAD2L1. Species sequence homology: Bovine, canine, mouse, porcine and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-KVNSMVAYKIPVND, from human MAD2L1, at C-terminal (NP_002349.1). Specificity: Recognizes human MAD2L1. Species sequence homology: Bovine, canine, mouse, porcine and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Li Y, Benezra R. Identification of a human mitotic checkpoint gene: hsMAD2. Science. 1996 Oct 11;274(5285):246-8.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/47/M1499-15J_1.jpg