Leukocyte Specific Protein 1 (LSP1) | US Biological L2030 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Leukocyte Specific Protein 1 (LSP1)

catalog :

L2030

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

L2030

Product wo Prefix :

Leukocyte Specific Protein 1 (LSP1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ul

Isotype :

IgG

Desc1 :

LSP1 is a 52kD leukocyte-specific protein expressed in B cells, T cells, macrophages and neutrophils (1). The protein binds F-actin through its carboxy-terminal actin-binding repeat and regulates cytoskeletal-related cellular movement such as polarization, chemotaxis and locomotion (2–4). LSP1 is a phospho-protein and has been identified as a major substrate of MAP kinase and PKC in lymphocytes and neutrophils (5–7). The phosphorylation is possibly related to its cytoskeletal regulation function. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to residues surrounding aa37-48 of human LSP1.

Specificity :

Recognizes endogenous levels of human LSP1 protein independent of phosphorylation at ~52kD. Species Crossreactivity: mouse and rat.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.

Concentration :

Not determined

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: Not determined Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: Synthetic peptide corresponding to residues surrounding aa37-48 of human LSP1. Specificity: Recognizes endogenous levels of human LSP1 protein independent of phosphorylation at ~52kD. Species Crossreactivity: mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Reference :

1. Li, Y., et al., J. Immunol. 155: 3563-3569 (1995). 2. Zhang, Q., et al., J. Immunol. 165: 2052-2058 (2000). 3. Li, Y., et al., Blood 96: 1100-1105 (2000). 4. Wang, C., et al., J. Immunol. 169: 415-423 (2002). 5. Huang, C.K., et al., J. Biol. Chem. 272: 17-19 (1997). 6. Matsumoto, N., et al., J. Biochem. (Tokyo) 117: 222-229 (1995). 7. Carballo, E., et al., J. Immunol. 156: 1709-1713 (1996).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/14/L2030_1.jpg