Keratin 15 (KRT15, CK15, CK-15, Cytokeratin-15, K15, K1CO, Keratin, type I cytoskeletal 15, KRTB) | US Biological K0199-18A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Keratin 15 (KRT15, CK15, CK-15, Cytokeratin-15, K15, K1CO, Keratin, type I cytoskeletal 15, KRTB)

catalog :

K0199-18A

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10F606

reactivity :

human

product information

Catalog Number :

K0199-18A

Product wo Prefix :

Keratin 15 (KRT15, CK15, CK-15, Cytokeratin-15, K15, K1CO, Keratin, type I cytoskeletal 15, KRTB)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

10F606

Isotype :

IgG1

Desc1 :

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype. Applications: Suitable for use in ELISA, Western Blot. and Immunofluorescence.Other applications not tested. Recommended Dilution: ELISA: 1:10,000 Western Blot: 1:500-1:2000 Immunofluorescence: 1:200-1:800 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo

Immunogen :

Purified recombinant fragment of KRT15 expressed in E. coli.

Specificity :

Recognizes human Metadherin (MTDH) at 49kD. Species Crossreactivity: mouse.

Purity :

Ascites

Form :

Supplied as liquid, 0.04% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 10F606 Host: mouse Source: human Concentration: Not determined Form: Supplied as liquid, 0.04% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of KRT15 expressed in E. coli. Specificity: Recognizes human Metadherin (MTDH) at 49kD. Species Crossreactivity: mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IF WB

Storage Temperature :

-20°C

Reference :

1. J Invest Dermatol. 1999. 112(3):362-9, 2. Exp Cell Res. 2006. 254(1):80-90, 3. Mol Cell Biol. 2000. 24(8):3168-79.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/27/K0199-18A_1.jpg