KPNA2 (Importin Subunit alpha-2, RAG Cohort Protein 1, SRP1-alpha, Karyopherin Subunit alpha-2, RCH1, SRP1) | US Biological K0102-06K product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

KPNA2 (Importin Subunit alpha-2, RAG Cohort Protein 1, SRP1-alpha, Karyopherin Subunit alpha-2, RCH1, SRP1)

catalog :

K0102-06K

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

K0102-06K

Product wo Prefix :

KPNA2 (Importin Subunit alpha-2, RAG Cohort Protein 1, SRP1-alpha, Karyopherin Subunit alpha-2, RCH1, SRP1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ul

Isotype :

IgG

Desc1 :

KPNA2 is a 58-60kD member of the Importin alpha family of proteins. It is ubiquitously expressed, and found in both nucleus and cytoplasm. KPNA2 functions as a cargo carrier that transports various complexes from cytoplasm into nucleus. For the MRN DNA repair complex, KPNA2 first binds to NBS1, and then to Importin b1, which mediates movement through the nuclear pore. Human KPNA2 is 529aa in length. It contains an N-terminal IBB/Importin b domain aa2-60, ten Armadillo repeats that bind "cargo" aa71-496 and two intervening NLS binding sites. There is one splice variant that shows a deletion of aa72-310, coupled to an 11aa substitution for aa389-406. Over aa1-132, human KPNA2 shares 94aa identity with mouse KPNA2. Applications: Suitable for use in Western Blot and immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to human KPNA2.

Specificity :

Recognizes human KPNA2.

Purity :

Purified by affinity chromatography.

Form :

Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 30% glycerol.

Concentration :

Not determined

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: Not determined Form: Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 30% glycerol. Purity: Purified by affinity chromatography. Immunogen: Synthetic peptide corresponding to human KPNA2. Specificity: Recognizes human KPNA2. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

IP WB

Storage Temperature :

-20°C