antibody

IGFBP7 (Insulin-like Growth Factor-binding Protein 7, IBP-7, IGF-binding Protein 7, IGFBP-7, IGFBP-rP1, TAF, MAC25 Protein, PGI2-stimulating Factor, Prostacyclin-stimulating Factor, Tumor-derived Adhesion Factor, TAF, MAC25, PSF)

I7661-17C2

100 ug

polyclonal

domestic goat

nonconjugated

IGFBP7 (Insulin-like Growth Factor-binding Protein 7, IBP-7, IGF-binding Protein 7, IGFBP-7, IGFBP-rP1, TAF, MAC25 Protein, PGI2-stimulating Factor, Prostacyclin-stimulating Factor, Tumor-derived Adhesion Factor, TAF, MAC25, PSF)

goat

Pab

Antibodies

100 ug

IgG

IGFBP-7 (insulin-like growth factor binding protein-7) is a secreted protein which belongs to a family of IGF-BPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II. IGFBP-7 is expressed in many tumor types and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Bo Hu

Synthetic peptide corresponding to C-NKVKRGHYGVQRTE, from IGFBP7, at the internal region of the protein (NP_001544.1).

Recognizes IGFBP7. Species sequence homology: Bovine and human.

Purified by immunoaffinity chromatography

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

~0.5mg/ml

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to C-NKVKRGHYGVQRTE, from IGFBP7, at the internal region of the protein (NP_001544.1). Specificity: Recognizes IGFBP7. Species sequence homology: Bovine and human. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E

-20°C

1. Ruan W, Xu E, Xu F, Ma Y, Deng H, Huang Q, Lv B, Hu H, Lin J, Cui J, Di M, Dong J, Lai M. IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis. Cancer Biol Ther. 2007 Mar;6(3):354-9. Epub 2007 Mar 12.