ICOS Ligand (CD275, Inducible T cell Co-stimulator Ligand, B7-H2, B7 Homolog 2, B7-like Protein Gl50, B7 Related Protein 1, B7H2, B7RP-1, B7RP1, GL50, ICOS LG , ICOSLG, KIAA0653, LICOS, Transmembrane Protein B7 H2 ICOS Ligand) | US Biological I0650-01H product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ICOS Ligand (CD275, Inducible T cell Co-stimulator Ligand, B7-H2, B7 Homolog 2, B7-like Protein Gl50, B7 Related Protein 1, B7H2, B7RP-1, B7RP1, GL50, ICOS LG , ICOSLG, KIAA0653, LICOS, Transmembrane Protein B7 H2 ICOS Ligand)

catalog :

I0650-01H

quantity :

500 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8H103

reactivity :

human

product information

Catalog Number :

I0650-01H

Product wo Prefix :

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

500 ug

Clone # USB :

8H103

Isotype :

IgG2b

Desc1 :

ICOS Ligand, also known as B7-related protein 1 (B7RP-1), is a costimulatory molecule that serves as a ligand for ICOS (Inducible Co-Stimulator). Applications: Suitable for use in Neutralization, ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Neutralization: 1-4ug/ml yields one-half maximal inhibition (ND50) of the cell surface ICOS Ligand in the presence of 20ng/ml of anti-human CD3 and 3ug/ml of recombinant human B7-H2/Fc, using B7-H2-dependent proliferation of PHA activated human T cells as an assay. Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Hybridoma: Hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human ICOS Ligand extracellular domain. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

B7RP-1, B7h, LICOS, GL50

Immunogen :

Recombinant protein corresponding to aa19-258 from human ICOS Ligand, expressed in NS0 cells. Swiss Prot#: O75144

Specificity :

Recognizes human ICOS Ligand. No crossreactivity with recombinant human B7-1, B7-2, B7-H1, B7-H3, recombinant mouse B7-H2 or PD-L2.

Purity :

Purified by Protein G affinity chromatography from cell culture supernatant. Endotoxin: <0.1EU/ug (LAL)

Form :

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.

Concentration :

~0.5mg/ml (after reconstitution)

Desc2 :

Product Type: Mab Isotype: IgG2b Clone No: 8H103 Host: mouse Source: human Concentration: ~0.5mg/ml (after reconstitution) Form: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS. Purity: Purified by Protein G affinity chromatography from cell culture supernatant. Endotoxin: <0.1EU/ug (LAL) Immunogen: Recombinant protein corresponding to aa19-258 from human ICOS Ligand, expressed in NS0 cells. Swiss Prot#: O75144 Specificity: Recognizes human ICOS Ligand. No crossreactivity with recombinant human B7-1, B7-2, B7-H1, B7-H3, recombinant mouse B7-H2 or PD-L2. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E N WB

Storage Temperature :

-20°C

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/29/I0650-01H_1.jpg