Herstatin | US Biological H2034-31A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Herstatin

catalog :

H2034-31A

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7H246

reactivity :

human

product information

Catalog Number :

H2034-31A

Product wo Prefix :

Herstatin

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ug

Clone # USB :

7H246

Isotype :

IgG2b

Desc1 :

Herstatin is a secreted 68kD glycoprotein encoded by an alternate transcript of the HER-2/neu (ErbB-2) gene containing the N-terminal 304 amino acids (aa) of subdomain I and II, and 79 intron-encoded aa at the C-terminus. It is an endogenous inhibitor of the EGF receptor family that disrupts receptor interactions and inhibits growth of tumor cells that overexpress HER-2. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Immunogen :

Recombinant protein corresponding to Thr23-Gly419 from human Herstatin, expressed in Sf21cells (AAD56009).

Specificity :

Recognizes human Herstatin. No cross reactivity with recombinant human EGF R or recombinant human ErbB3.

Purity :

Purified by Protein G affinity chromatography from culture supernatant.

Form :

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.

Concentration :

~0.5mg/ml (after reconstitution)

Desc2 :

Product Type: Mab Isotype: IgG2b Clone No: 7H246 Host: mouse Source: human Concentration: ~0.5mg/ml (after reconstitution) Form: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS. Purity: Purified by Protein G affinity chromatography from culture supernatant. Immunogen: Recombinant protein corresponding to Thr23-Gly419 from human Herstatin, expressed in Sf21cells (AAD56009). Specificity: Recognizes human Herstatin. No cross reactivity with recombinant human EGF R or recombinant human ErbB3. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C