Hsp27 (HSPB1, Heat Shock Protein beta-1, HspB1, Heat Shock 27kD Protein, HSP 27) | US Biological H1830-59 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Hsp27 (HSPB1, Heat Shock Protein beta-1, HspB1, Heat Shock 27kD Protein, HSP 27)

catalog :

H1830-59

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat

product information

Catalog Number :

H1830-59

Product wo Prefix :

Hsp27 (HSPB1, Heat Shock Protein beta-1, HspB1, Heat Shock 27kD Protein, HSP 27)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Hsp27 exhibits a chaperone-like activity by serving as a site where unfolding proteins may bind until ATP and Hsp70-dependent refolding can occur. Hsp27 is believed to protect cells by enhancing cellular glutathione levels and elevated glutathione levels have been measured in cells overexpressing Hsp27. Data from studies using wild-type Hsp27 and mutant forms in which the serine phosphorylation sites were mutated to alanines, glycines or aspartates, have shown that cellular glutathione levels depend on the oligomerization of Hsp27. Recent findings indicate that Hsp27 is also a negative regulator of cytochrome c-dependent activation of procaspase-3. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Synthetic peptide corresponding to aa193 from rat Hsp2.

Specificity :

Recognizes rat Hsp27 at ~27kD.

Purity :

Purified by affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: rat Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol. Purity: Purified by affinity chromatography. Immunogen: Synthetic peptide corresponding to aa193 from rat Hsp2. Specificity: Recognizes rat Hsp27 at ~27kD. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/29/H1830-59_1.jpg