antibody

Gapdh (Glyceraldehyde-3-phosphate Dehydrogenase, GAPDH, 38kD BFA-dependent ADP-ribosylation Substrate, BARS-38, Peptidyl-cysteine S-nitrosylase GAPDH, Gapd)

G8140-12B

100 ug

polyclonal

domestic rabbit

nonconjugated

Gapdh (Glyceraldehyde-3-phosphate Dehydrogenase, GAPDH, 38kD BFA-dependent ADP-ribosylation Substrate, BARS-38, Peptidyl-cysteine S-nitrosylase GAPDH, Gapd)

rabbit

Pab

Antibodies

100 ug

IgG

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. Besides functioning as a glycolytic enzyme in cytoplasm, evidence suggests that mammalian GAPDH is also involved in a great number of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication and DNA repair. During the last decade, many findings have been made concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death and age-related neuronal diseases such as Alzheimer’s and Huntington’s. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kD subunits. The molecular weight for GAPDH is 146kD. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Mo Rt

Synthetic peptide corresponding to aa317 from rat GADPH (XP_214281.3).

Recognizes rat GAPDH at ~36kD. Species Crossreactivity: human and mouse.

Purified by affinity chromatography.

Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.

~0.5mg/ml

Product Type: Pab Isotype: IgG Host: rabbit Source: rat Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol. Purity: Purified by affinity chromatography. Immunogen: Synthetic peptide corresponding to aa317 from rat GADPH (XP_214281.3). Specificity: Recognizes rat GAPDH at ~36kD. Species Crossreactivity: human and mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

WB

-20°C

https://usbio-images.r.worldssl.net/prodimages/35/G8140-12B_1.jpg