antibody

FBXL6 (F-box/LRR-repeat Protein 6, F-box and Leucine-rich Repeat Protein 6, F-box Protein FBL6, FBL6A, FBL6)

F0024-01A1

100 ug

polyclonal

domestic goat

nonconjugated

human, mouse

FBXL6 (F-box/LRR-repeat Protein 6, F-box and Leucine-rich Repeat Protein 6, F-box Protein FBL6, FBL6A, FBL6)

goat

Pab

Antibodies

100 ug

IgG

This gene encodes a member of the F-box protein family which is characterized by an approximately 40aa motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu Mo

Synthetic peptide corresponding to CLEQLLTSPSPS, from FBXL6, at C-terminal (NP_036294.1, NP_078831.3).

Recognizes FBXL6. Species sequence homology: Human and mouse.

Purified by immunoaffinity chromatography

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

~0.5mg/ml

Product Type: Pab Host: goat Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to CLEQLLTSPSPS, from FBXL6, at C-terminal (NP_036294.1, NP_078831.3). Specificity: Recognizes FBXL6. Species sequence homology: Human and mouse. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E

-20°C

1. Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW. A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2.